product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human KIR2DL5/CD158f Fc Chimera Protein, CF
catalog :
6634-KR-050
quantity :
50 ug
price :
456 USD
more info or order :
citations: 1
Reference
Fittje P, H x153 lzemer A, Garcia Beltran W, Vollmers S, Niehrs A, Hagemann K, et al. HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 2022;18:e1010572 pubmed publisher
product information
master code :
6634-KR
SKU :
6634-KR-050
product name :
Recombinant Human KIR2DL5/CD158f Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human KIR2DL5/CD158f Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL5/CD158f Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
KIR2DL5/CD158f
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
66 kDa, reducing conditions
theoretical molecular weight :
50.1 kDa (monomer)
gene symbol :
KIR2DL5A
details of functionality :
Measured by its ability to bind HLA on MDA-MB-231 human breast cancer cells. The ED50 for this effect is 0.9-3.6 ╡g/mL. . Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_065396
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human KIR2DL5/CD158f protein Human KIR2DL5 (His22 - His240) Accession # NP_065396 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
456 USD
alt names :
CD158F, CD158F1, killer cell immunoglobulin-like receptor 2DL5A, killer cell immunoglobulin-like receptor KIR2DL5A, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A, killer-cell Ig-like receptor, KIR2DL5, KIR2DL5.1, KIR2DL5.3, KIR2DL5A, KIR2DL5B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.