product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IGF-I R/IGF1R Protein
catalog :
6630-GR-025
quantity :
25 ug
price :
394 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Yogi A, Hussack G, van Faassen H, Haqqani A, Delaney C, Brunette E, et al. Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor. Pharmaceutics. 2022;14: pubmed publisher
Solomon V, Alizadeh E, Bernhard W, Makhlouf A, Hartimath S, Hill W, et al. Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer. Sci Rep. 2020;10:18549 pubmed publisher
De Giovanni C, Landuzzi L, Palladini A, Ianzano M, Nicoletti G, Ruzzi F, et al. Cancer Vaccines Co-Targeting HER2/Neu and IGF1R. Cancers (Basel). 2019;11: pubmed publisher
product information
brand :
R&D Systems
master code :
6630-GR
SKU :
6630-GR-025
product name :
Recombinant Mouse IGF-I R/IGF1R Protein
description :
The Recombinant Mouse IGF-I R/IGF1R Protein from R&D Systems is derived from CHO. The Recombinant Mouse IGF-I R/IGF1R Protein has been validated for the following applications: Bioactivity.
target :
IGF-I R/IGF1R
category :
Proteins and Enzymes
unit sizes :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
160-170 kDa, 120-130 kDa 45-52 kDa, reducing conditions.
theoretical molecular weight :
104.5 kDa (single chain), 80.7 kDa ( alpha subunit) 23.2 kDa ( beta subunit)
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Mouse (rm) IGF-I R/IGF1R is present at 0.5 µg/mL, the concentration of rmIGF-I that produces 50% of the optimal binding response is found to be approximately 10-60 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q60751
applications :
Bioactivity
source :
CHO-derived Recombinant Mouse IGF-I R/IGF1R Protein
USD :
394 USD
alt names :
CD221, CD221 antigen, EC 2.7.10, EC 2.7.10.1, IGF1R, IGF-1R, IGF-I receptor, IGFIR, IGF-IR, IGFR, insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, JTK13, MGC142170, MGC142172, MGC18216, soluble IGF1R variant 1, soluble IGF1R variant 2
storage :
12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.