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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Protein, CF
catalog :
663-FR-050
quantity :
50 ug
price :
431 USD
more info or order :
citations: 2
Reference
Manzano Núñez F, Arámbul Anthony M, Galán Albiñana A, Leal Tassias A, Acosta Umanzor C, Borreda Gascó I, et al. Insulin resistance disrupts epithelial repair and niche-progenitor Fgf signaling during chronic liver injury. PLoS Biol. 2019;17:e2006972 pubmed publisher
Tao C, Zhang X. Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016;17:1832-1844 pubmed publisher
product information
master code :
663-FR
SKU :
663-FR-050
product name :
Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR2 alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
100 kDa, reducing conditions
theoretical molecular weight :
66 kDa (monomer)
gene symbol :
FGFR2
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1.00-3.00 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
CAA39654.1
applications :
Bioactivity
source long :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived human FGFR2 alpha protein Human FGF R2 alpha (IIIb) (Arg22-Glu378) Accession # CAA39654.1 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
Sf 21 (baculovirus)
USD :
431 USD
alt names :
BBDS;BEK;BFR-1;CD332;CEK3;CFD1;ECT1;Fibroblast growth factor receptor;Fibroblast growth factor receptor 2;JWS;KGFR;K-SAM;Receptor protein-tyrosine kinase;TK14;TK25, CD332, FGF R2, FGF R2a
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.