Recombinant Human Dkk-2 Protein | R&D Systems 6628-DK-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Dkk-2 Protein

catalog :

6628-DK-010

quantity :

10 ug

price :

400 USD

citations: 4

Reference
Marta C, Adrian M, Jorge F, Francisco A, De Miguel M. Improvement of an Effective Protocol for Directed Differentiation of Human Adipose Tissue-Derived Adult Mesenchymal Stem Cells to Corneal Endothelial Cells. Int J Mol Sci. 2021;22: pubmed publisher
Ali M, Khan S, Gottsch J, Hutchinson E, Khan A, Riazuddin S. Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty. Stem Cell Reports. 2021;16:2320-2335 pubmed publisher
Ali M, Khan S, Vasanth S, Ahmed M, Chen R, Na C, et al. Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2018;59:2437-2444 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher

product information

master code :

6628-DK

SKU :

6628-DK-010

product name :

Recombinant Human Dkk-2 Protein

unit size :

10 ug

description :

The Recombinant Human Dkk-2 Protein from R&D Systems is derived from CHO. The Recombinant Human Dkk-2 Protein has been validated for the following applications: Bioactivity.

target :

Dkk-2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and EDTA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

32-36 kDa, reducing conditions

theoretical molecular weight :

25.8 kDa

gene symbol :

DKK2

details of functionality :

Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. Recombinant Human Dkk-2 (Catalog # 6628-DK) inhibits a constant dose of 500 ng/mL of Recombinant Human Wnt-3a (Catalog # 5036-WN ). The ED50 for this effect is 50-300 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human Dkk-2 Protein Bioactivity

accessionNumbers :

NP_055236

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human Dkk-2 protein Met1-Ile259

source short :

CHO

USD :

400 USD

alt names :

dickkopf (Xenopus laevis) homolog 2, dickkopf 2, dickkopf homolog 2 (Xenopus laevis), dickkopf related protein-2, Dickkopf-2, dickkopf-related protein 2, Dkk2, DKK-2, hDkk-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.