Recombinant Human Dkk-2 Protein, CF | R&D Systems 6628-DK-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Dkk-2 Protein, CF

catalog :

6628-DK-010/CF

quantity :

10 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Marta C, Adrian M, Jorge F, Francisco A, De Miguel M. Improvement of an Effective Protocol for Directed Differentiation of Human Adipose Tissue-Derived Adult Mesenchymal Stem Cells to Corneal Endothelial Cells. Int J Mol Sci. 2021;22: pubmed publisher
Ali M, Khan S, Gottsch J, Hutchinson E, Khan A, Riazuddin S. Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty. Stem Cell Reports. 2021;16:2320-2335 pubmed publisher
Ali M, Khan S, Vasanth S, Ahmed M, Chen R, Na C, et al. Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2018;59:2437-2444 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher

image

image 1 :

Recombinant Human Dkk-2 Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

6628-DK/CF

SKU :

6628-DK-010/CF

product name :

Recombinant Human Dkk-2 Protein, CF

Description :

The Recombinant Human Dkk-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Dkk-2 Protein, CF has been validated for the following applications: Bioactivity.

target :

Dkk-2

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

32-36 kDa, reducing conditions

theoretical molecular weight :

25.8 kDa

gene symbol :

DKK2

details of functionality :

Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. Recombinant Human Dkk-2 (Catalog # 6628-DK/CF) inhibits a constant dose of 500 ng/mL of Recombinant Human Wnt-3a (Catalog # 5036-WN ). The ED50 for this effect is 50-300 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_055236

applications :

Bioactivity

source :

CHO-derived Recombinant Human Dkk-2 Protein

USD :

396 USD

alt names :

dickkopf (Xenopus laevis) homolog 2, dickkopf 2, dickkopf homolog 2 (Xenopus laevis), dickkopf related protein-2, Dickkopf-2, dickkopf-related protein 2, Dkk2, DKK-2, hDkk-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage