product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein, CF
catalog :
661-FR-050
quantity :
50 ug
price :
377 USD
more info or order :
citations: 9
Reference |
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Yang L, Hansen Falkesgaard M, Thulstrup P, Walmod P, Lo Leggio L, Krighaar Rasmussen K. Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3. Peerj. 2017;5:e3550 pubmed publisher
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Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007;109:1363-72 pubmed
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Murase S, McKay R. A specific survival response in dopamine neurons at most risk in Parkinson's disease. J Neurosci. 2006;26:9750-60 pubmed
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Steinberg Z, Myers C, Heim V, Lathrop C, Rebustini I, Stewart J, et al. FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis. Development. 2005;132:1223-34 pubmed
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Kessaris N, Jamen F, Rubin L, Richardson W. Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors. Development. 2004;131:1289-98 pubmed
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Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein Bioactivity
product information
brand :
R&D Systems
master code :
661-FR
SKU :
661-FR-050
product name :
Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein, CF
description :
The Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR1 beta
category :
Proteins and Enzymes
unit sizes :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
90-95 kDa, reducing conditions
theoretical molecular weight :
56 kDa (monomer)
gene symbol :
FGFR1
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1-3 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_075594
applications :
Bioactivity
source :
NS0-derived Recombinant Human FGFR1 beta (IIIc) Fc Chimera Protein, CF
USD :
377 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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