Recombinant Mouse Pleiotrophin/PTN Protein, CF | R&D Systems 6580-PL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Pleiotrophin/PTN Protein, CF

catalog :

6580-PL

quantity :

50 ug

price :

299 USD

citations: 3

Reference
Himburg H, Roos M, Fang T, Zhang Y, Termini C, Schlussel L, et al. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020;130:315-328 pubmed publisher
Henry F, Sugino K, Tozer A, Branco T, Sternson S. Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss. elife. 2015;4: pubmed publisher
Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G. The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-? signaling. Dev Biol. 2013;377:415-27 pubmed publisher

product information

brand :

R&D Systems

master code :

6580-PL

SKU :

6580-PL-050

product name :

Recombinant Mouse Pleiotrophin/PTN Protein, CF

description :

The Recombinant Mouse Pleiotrophin/PTN Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse Pleiotrophin/PTN Protein, CF has been validated for the following applications: Bioactivity.

target :

Pleiotrophin/PTN

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

19 kDa, reducing conditions

theoretical molecular weight :

15.3 kDa

details of functionality :

Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cerebral cortical neurons. Muramatsu, H. and T. Muramatsu (1991) Biochem. Biophys. Res. Commu. 177 :652. Optimal neurite outgrowth was observed when neurons were plated on 96 well culture plates that had been pre-coated with 100 µL/well of recombinant mouse Pleiotrophin at 3-8 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

6580-PL

accessionNumbers :

P63089

applications :

Bioactivity

source :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse Pleiotrophin/PTN protein Met1-Asp168

2020 USD :

299

2021 USD :

299 USD

alt names :

HARP, HBBM, HB-GAM, HBGF8, HBNF, HBNF1, HBNF-1, Heparin-binding brain mitogen, HNGF-8, NEGF1HBGF-8, neurite growth-promoting factor 1, neurite growth-promoting factor1), OSF-1, Osteoblast-specific factor 1, pleiotrophin, PTN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.