product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF
catalog :
658-FR-050
quantity :
50 ug
price :
407 USD
more info or order :
citations: 5
Reference |
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Martinez Torrecuadrada J, Cifuentes G, López Serra P, Saenz P, Martinez A, Casal J. Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation. Clin Cancer Res. 2005;11:6280-90 pubmed
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Kessaris N, Jamen F, Rubin L, Richardson W. Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors. Development. 2004;131:1289-98 pubmed
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product information
master code :
658-FR
SKU :
658-FR-050
product name :
Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR1 alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
100-110 kDa, reducing conditions
theoretical molecular weight :
66 kDa (monomer)
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1-3áng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_056934
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human FGFR1 alpha protein Human FGF R1 alpha (IIIc) (Arg22-Glu374) Accession # NP_056934 IEGRDMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
407 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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