Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF | R&D Systems 6578-EN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF

catalog :

6578-EN

quantity :

25 ug

price :

339 USD

citations: 2

Reference
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher

product information

brand :

R&D Systems

master code :

6578-EN

SKU :

6578-EN-025

product name :

Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF

description :

The Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Endoglin/CD105

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

100-115 kDa, reducing conditions

theoretical molecular weight :

87.3 kDa (monomer)

gene symbol :

ENG

details of functionality :

Measured by its ability to inhibit BMP-10-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 0.3-1.2 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

6578-EN

accessionNumbers :

P17813

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human Endoglin/CD105 protein Human Endoglin (Met1-Gly586) Accession # P17813 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

2020 USD :

339

2021 USD :

339 USD

alt names :

CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.