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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGFR1 alpha (IIIb) Fc Chimera Protein, CF
catalog :
655-FR-050
quantity :
50 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher
Lee H, Raiker S, Venkatesh K, Geary R, Robak L, Zhang Y, et al. Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength. J Neurosci. 2008;28:2753-65 pubmed publisher
Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007;109:1363-72 pubmed
product information
master code :
655-FR
SKU :
655-FR-050
product name :
Recombinant Human FGFR1 alpha (IIIb) Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human FGFR1 alpha (IIIb) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR1 alpha (IIIb) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR1 alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
110-120 kDa, reducing conditions
theoretical molecular weight :
66 kDa (monomer)
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1-3áng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_056934
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human FGF R1 alpha protein Human FGF R1 alpha (IIIb) (Arg22 - Lys310) Accession # NP_056934 IIIb Ig domain (His1 - Pro47) Accession # AAB19502 Human FGF R1 alpha (IIIb) (Ala359 - Glu374) Accession # NP_056934 IEGRDMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
400 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.