product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine IL-4 Protein, CF
catalog :
654-P4-025/CF
quantity :
25 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 18
Reference
Oreskovic Z, Lev xe1 L, Chlebov xe1 K, Hlavov xe1 K, Tesa x159 xed k R, Gebauer J, et al. Effects of IFNγ and IL4 rich microenvironment on porcine monocyte-derived dendritic cell activation in vitro. Res Vet Sci. 2022;145:54-62 pubmed publisher
Zheng L, Zhao F, Ru J, Liu L, Wang Z, Wang N, et al. Evaluation of the Effect of Inactivated Transmissible Gastroenteritis Virus Vaccine with Nano Silicon on the Phenotype and Function of Porcine Dendritic Cells. Viruses. 2021;13: pubmed publisher
Hamid B, Schlosser Brandenburg J, Bechtold L, Ebner F, Rausch S, Hartmann S. Early Immune Initiation by Porcine Cells following Toxoplasma gondii Infection versus TLR Ligation. Microorganisms. 2021;9: pubmed publisher
Qu X, Neuhoff C, Cinar M, Pröll M, Tholen E, Tesfaye D, et al. Epigenetic Modulation of TLR4 Expression by Sulforaphane Increases Anti-Inflammatory Capacity in Porcine Monocyte-Derived Dendritic Cells. Biology (Basel). 2021;10: pubmed publisher
Zheng D, Wang Z, Sui L, Xu Y, Wang L, Qiao X, et al. Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response. Cytokine. 2021;144:155581 pubmed publisher
Hall S, Ison S, Owles C, Coe J, Sandercock D, Zanella A. Development and validation of a multiplex fluorescent microsphere immunoassay assay for detection of porcine cytokines. MethodsX. 2019;6:1218-1227 pubmed publisher
Linard C, Brachet M, l Homme B, Strup Perrot C, Busson E, Bonneau M, et al. Long-term effectiveness of local BM-MSCs for skeletal muscle regeneration: a proof of concept obtained on a pig model of severe radiation burn. Stem Cell Res Ther. 2018;9:299 pubmed publisher
Franzoni G, Graham S, Sanna G, Angioi P, Fiori M, Anfossi A, et al. Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence. Vet Microbiol. 2018;216:190-197 pubmed publisher
Singleton H, Graham S, Frossard J, Bodman Smith K, Steinbach F. Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10. Virology. 2018;517:199-207 pubmed publisher
Ahlberg V, Hjertner B, Wallgren P, Hellman S, Lövgren Bengtsson K, Fossum C. Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs. Vet Res. 2017;48:30 pubmed publisher
Elahi S, Thompson D, Van Kessel J, Babiuk L, Gerdts V. Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets. Infect Immun. 2017;85: pubmed publisher
Fan B, Liu X, Bai J, Li Y, Zhang Q, Jiang P. The 15N and 46R Residues of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Enhance Regulatory T Lymphocytes Proliferation. PLoS ONE. 2015;10:e0138772 pubmed publisher
Rodríguez Gómez I, Käser T, Gómez Laguna J, Lamp B, Sinn L, Rümenapf T, et al. PRRSV-infected monocyte-derived dendritic cells express high levels of SLA-DR and CD80/86 but do not stimulate PRRSV-naïve regulatory T cells to proliferate. Vet Res. 2015;46:54 pubmed publisher
Qu X, Pröll M, Neuhoff C, Zhang R, Cinar M, Hossain M, et al. Sulforaphane epigenetically regulates innate immune responses of porcine monocyte-derived dendritic cells induced with lipopolysaccharide. PLoS ONE. 2015;10:e0121574 pubmed publisher
Kyrova K, Stepanova H, Rychlik I, Polansky O, Leva L, Sekelova Z, et al. The response of porcine monocyte derived macrophages and dendritic cells to Salmonella Typhimurium and lipopolysaccharide. BMC Vet Res. 2014;10:244 pubmed publisher
Sang Y, Brichalli W, Rowland R, Blecha F. Genome-wide analysis of antiviral signature genes in porcine macrophages at different activation statuses. PLoS ONE. 2014;9:e87613 pubmed publisher
Black S, Schott M, Batdorf B, Benson B, Rutherford M, Levay Young B, et al. IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis. Eur J Immunol. 2010;40:803-12 pubmed publisher
Azevedo M, Yuan L, Pouly S, Gonzales A, Jeong K, Nguyen T, et al. Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus. J Virol. 2006;80:372-82 pubmed
product information
brand :
R&D Systems
master code :
654-P4/CF
SKU :
654-P4-025/CF
product name :
Recombinant Porcine IL-4 Protein, CF
unit size :
25 ug
seo description :
The Recombinant Porcine IL-4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Porcine IL-4 Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-4
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Porcine
theoretical molecular weight :
12.5 kDa
gene symbol :
IL4
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.15-0.75 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q04745
applications :
Bioactivity
source :
E. coli-derived Recombinant Porcine IL-4 Protein, CF
USD :
456 USD
alt names :
B cell growth factor 1, BCDF, B-cell stimulatory factor 1, BCGF1, BCGF-1, binetrakin, BSF1, BSF-1, IL4, IL-4B_cell stimulatory factor 1, IL4E12, interleukin 4, interleukin-4, Lymphocyte stimulatory factor 1, MGC79402, Pitrakinra
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.