Recombinant Human TROP-2 Fc Chimera Protein, CF | R&D Systems 650-T2-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TROP-2 Fc Chimera Protein, CF

catalog :

650-T2-100

quantity :

100 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Guerra E, Trerotola M, Relli V, Lattanzio R, Ceci M, Boujnah K, et al. The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody. Cancers (Basel). 2023;15: pubmed publisher
Uemachi H, Kasahara Y, Tanaka K, Okuda T, Yoneda Y, Obika S. Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity. Pharmaceutics. 2021;13: pubmed publisher
Leitner J, Rieger A, Pickl W, Zlabinger G, Grabmeier Pfistershammer K, Steinberger P. TIM-3 does not act as a receptor for galectin-9. PLoS Pathog. 2013;9:e1003253 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

650-T2

SKU :

650-T2-100

product name :

Recombinant Human TROP-2 Fc Chimera Protein, CF

Description :

The Recombinant Human TROP-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TROP-2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TROP-2

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

70-80 kDa, reducing conditions

theoretical molecular weight :

49.2 kDa (monomer)

gene symbol :

TACSTD2

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells or LS180 human colorectal adenocarcinoma cells. When 1 x 104 to 5 x 104 cells/well are added to Recombinant Human TROP-2 Fc Chimera coated plates (10 µg/mL with 100 µL/well), 45% cells will adhere after 1 hour incubation. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P09758.3

applications :

Bioactivity

source :

NS0-derived Recombinant Human TROP-2 Fc Chimera Protein

USD :

434 USD

alt names :

Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, gp50, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, T16, TACSTD2, TROP2, TROP2GA7331, tumor-associated calcium signal transducer 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage