Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed) | R&D Systems 6449-TEC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed)

catalog :

6449-TEC

quantity :

10 ug

price :

329 USD

citations: 1

Reference
Shang W, Zhao L, Dong X, Zhao Z, Li J, Zhang B, et al. Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways. Mol Med Rep. 2016;14:3620-6 pubmed publisher

product information

brand :

R&D Systems

master code :

6449-TEC

SKU :

6449-TEC-010

product name :

Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed)

description :

The Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed) from R&D Systems is derived from E. coli. The Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed) has been validated for the following applications: Bioactivity.

target :

TRANCE/TNFSF11/RANK L

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MES and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

19 kDa, reducing conditions

theoretical molecular weight :

18.3 kDa

gene symbol :

TNFSF11

details of functionality :

Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 for this effect is 2-12 ng/mL

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

6449-TEC

accessionNumbers :

AAC51762

applications :

Bioactivity

source :

E. coli -derived human TRANCE/TNFSF11/RANK L protein Arg85-Asp245, with an N-terminal Met

2020 USD :

329

2021 USD :

329 USD

alt names :

CD254, CD254 antigen, ODF, OPGL, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK L, RANKL, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.