product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ACLP His-tag Protein, CF
catalog :
6425-AC-050
quantity :
50 ug
price :
710 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Sekiguchi S, Yorozu A, Okazaki F, Niinuma T, Takasawa A, Yamamoto E, et al. ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma. Cancers (Basel). 2023;15: pubmed publisher
product information
master code :
6425-AC
SKU :
6425-AC-050
product name :
Recombinant Human ACLP His-tag Protein, CF
unit size :
50 ug
description :
The Recombinant Human ACLP His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human ACLP His-tag Protein, CF has been validated for the following applications: Bioactivity.
target :
ACLP
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
160-180 kDa, reducing conditions
theoretical molecular weight :
130 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human LRP-6 Fc Chimera (Catalog # 1505-LR ) is coated at 2 ug/mL, 100 uL/well, Recombinant ACLP binds with an ED50 of 1-8 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human ACLP His-tag Protein Binding Activity
accessionNumbers :
Q8IUX7
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived human ACLP protein Gln26-Phe1158, with a C-terminal 10-His tag
source short :
HEK293
extended description :
ACLP activates canonical WNT/Beta-catenin signaling through Frizzeld-8 and LRP-6
USD :
710 USD
product details :
ACLP activates canonical WNT/Beta-catenin signaling through Frizzeld-8 and LRP-6
alt names :
ACLP, ACLPadipocyte enhancer binding protein 1, AE binding protein 1, AE-binding protein 1adipocyte enhancer-binding protein 1, AEBP1, Aortic carboxypeptidase-like protein, FLJ33612
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.