Recombinant Human Fucosyltransferase 7/FUT7 Protein, CF | R&D Systems 6409-GT-020 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Fucosyltransferase 7/FUT7 Protein, CF

catalog :

6409-GT-020

quantity :

20 ug

price :

567 USD

citations: 5

Reference
Donnelly C, Dykstra B, Mondal N, Huang J, Kaskow B, Griffin R, et al. Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression. Sci Rep. 2018;8:420 pubmed publisher
Wu Z, Person A, Anderson M, Burroughs B, Tatge T, Khatri K, et al. Imaging specific cellular glycan structures using glycosyltransferases via click chemistry. Glycobiology. 2017;: pubmed publisher
Silva M, Fung R, Donnelly C, Videira P, Sackstein R. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology. J Immunol. 2017;198:3576-3587 pubmed publisher
PachÃ³n PeÃ±a G, Donnelly C, Ruiz CaÃ±ada C, Katz A, FernÃ¡ndez Veledo S, Vendrell J, et al. A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells. 2017;35:1080-1092 pubmed publisher
Buffone A, Nasirikenari M, Manhardt C, Lugade A, Bogner P, Sackstein R, et al. Leukocyte-borne ?(1,3)-fucose is a negative regulator of ?2-integrin-dependent recruitment in lung inflammation. J Leukoc Biol. 2017;101:459-470 pubmed publisher

product information

master code :

6409-GT

SKU :

6409-GT-020

product name :

Recombinant Human Fucosyltransferase 7/FUT7 Protein, CF

unit size :

20 ug

description :

The Recombinant Human Fucosyltransferase 7/FUT7 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Fucosyltransferase 7/FUT7 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Fucosyltransferase 7/FUT7

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

40-45 kDa, reducing conditions

theoretical molecular weight :

36 kDa

gene symbol :

FUT7

details of functionality :

Measured by its ability to transfer fucose from GDP-fucose to fetal bovine fetuin. The specific activity is 175 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q11130

applications :

Enzyme Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived human Fucosyltransferase 7/FUT7 protein Ala36-Ala342 with a C-terminal 6-His tag

source short :

CHO

extended description :

FUT7 has been formulated so that it can be used in the cell surface glycoengineering of living cells, and does not affect cell viability or native phenotype apart from the intended impact on cell glycobiology.

USD :

567 USD

product details :

alt names :

alpha-(1,3)-fucosyltransferase, EC 2.4.1, EC 2.4.1.-, EC 2.4.1.65, FTVII, Fucosyltransferase 7, fucosyltransferase 7 (alpha (1,3) fucosyltransferase), Fucosyltransferase VII, Fuc-TVII, FucT-VII, FUT7, Galactoside 3-L-fucosyltransferase, Selectin ligand synthase, selectin-ligand synthase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.