Recombinant Mouse EphA3 Fc Chimera Protein, CF | R&D Systems 640-A3-200 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse EphA3 Fc Chimera Protein, CF

catalog :

640-A3-200

quantity :

200 ug

price :

318 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Itoh T, Hatano R, Horimoto Y, Yamada T, Song D, Otsuka H, et al. IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells. Cell Death Dis. 2021;12:520 pubmed publisher
Gerstmann K, Pensold D, Symmank J, Khundadze M, HÃ¼bner C, Bolz J, et al. Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015;142:140-50 pubmed publisher
Ono K, Clavairoly A, Nomura T, Gotoh H, Uno A, Armant O, et al. Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2. Development. 2014;141:2075-84 pubmed publisher
Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, et al. Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008;135:3281-90 pubmed publisher
Zhu Y, Guthrie S, Murakami F. Ephrin A/EphA controls the rostral turning polarity of a lateral commissural tract in chick hindbrain. Development. 2006;133:3837-46 pubmed
Janes P, Saha N, Barton W, Kolev M, Wimmer Kleikamp S, Nievergall E, et al. Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell. 2005;123:291-304 pubmed

product information

brand :

R&D Systems

master code :

640-A3

SKU :

640-A3-200

product name :

Recombinant Mouse EphA3 Fc Chimera Protein, CF

description :

The Recombinant Mouse EphA3 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse EphA3 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

EphA3

category :

Proteins and Enzymes

unit sizes :

200 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

110 kDa, reducing conditions

theoretical molecular weight :

86 kDa (monomer)

gene symbol :

Epha3

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmEphA3/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhEphrin A5 Fc Chimera with a linear range of 0.08-5 ng/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q8BRB1

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse EphA3 Fc Chimera Protein, CF

USD :

318 USD

alt names :

Cek4, EC 2.7.10, EC 2.7.10.1, EK4, EPH receptor A3, EphA3, EPH-like kinase 4, ephrin type-A receptor 3, ETK, hEK4, HEKETK1eph-like tyrosine kinase 1, human embryo kinase 1, Tyro4, TYRO4 protein tyrosine kinase, Tyrosine-protein kinase receptor ETK1, Tyrosine-protein kinase TYRO4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage