Recombinant Human QPCT Protein, CF | R&D Systems 6368-ZN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human QPCT Protein, CF

catalog :

6368-ZN-010

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Van Manh N, Hoang V, Ngo V, Kang S, Jeong J, Ha H, et al. Discovery of potent indazole-based human glutaminyl cyclase (QC) inhibitors as Anti-Alzheimer's disease agents. Eur J Med Chem. 2022;244:114837 pubmed publisher
Van Manh N, Hoang V, Ngo V, Ann J, Jang T, Ha J, et al. Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design. Eur J Med Chem. 2021;226:113819 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

6368-ZN

SKU :

6368-ZN-010

product name :

Recombinant Human QPCT Protein, CF

Description :

The Recombinant Human QPCT Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human QPCT Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Glutaminyl-peptide Cyclotransferase/QPCT

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

36-40 kDa, reducing conditions

theoretical molecular weight :

38 kDa

gene symbol :

QPCT

details of functionality :

Measured by its ability to convert Glutaminyl-AMC to pyroglutamyl-AMC. The specific activity is 550 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q16769

applications :

Enzyme Activity

source :

Sf 21 (baculovirus)-derived Recombinant Human QPCT Protein

USD :

423 USD

alt names :

EC 2.3.2.5, GCT, Glutaminyl cyclase, glutaminyl-peptide cyclotransferase, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, QCEC, sQC

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage