product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Integrin alpha 11 beta 1 Protein, CF
catalog :
6357-AB-050
quantity :
50 ug
price :
561 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Zeltz C, Alam J, Liu H, Erusappan P, Hoschuetzky H, Molven A, et al. α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration. Cancers (Basel). 2019;11: pubmed publisher
product information
master code :
6357-AB
SKU :
6357-AB-050
product name :
Recombinant Human Integrin alpha 11 beta 1 Protein, CF
unit size :
50 ug
description :
The Recombinant Human Integrin alpha 11 beta 1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 11 beta 1 Protein, CF has been validated for the following applications: Bioactivity.
target :
Integrin alpha 11 beta 1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
160-180 kDa 120-140 kDa, reducing conditions
theoretical molecular weight :
134.6 kDa ( alpha 11) 88.4 (▀1)
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized Collagen I at 10 ╡g/mL (100 ╡L/well) can bind Recombinant Human Integrin alpha 11▀1 with an apparent Kd 2.0 nM. Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 11 beta 1 protein Human Integrin alpha 11 (Phe23-Pro1141) (Leu524Arg) Accession # Q9UKX5 . GGGSGGGSGGGS Acidic Tail HHHHHH Human Integrin ▀1 (Gln21-Asp728) Accession # P05556 . GGGSGGGSGGGS Basic Tail N-terminus C-terminus
source short :
CHO
USD :
561 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.