This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF
catalog :
633-TR
quantity :
100 ug
price :
359 USD
citations: 3
Reference
Lee Y, Hwang E, Jang Y. Involvement of p38 Activation and Mitochondria in Death of Human Leukemia Cells Induced by an Agonistic Human Monoclonal Antibody Fab Specific to TRAIL Receptor 1. Int J Mol Sci. 2019;20: pubmed publisher
Gasparian M, Chernyak B, Dolgikh D, Yagolovich A, Popova E, Sycheva A, et al. Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5. Apoptosis. 2009;14:778-87 pubmed publisher
Newton P, Harrison P, Clulow S. A novel method for determination of the affinity of protein: protein interactions in homogeneous assays. J Biomol Screen. 2008;13:674-82 pubmed publisher
product information
brand :
R&D Systems
master code :
633-TR
SKU :
633-TR-100
product name :
Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF
description :
The Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TRAILR4/TNFRSF10D/DcR2
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
70-80 kDa, reducing conditions
theoretical molecular weight :
44.2 kDa (monomer)
gene symbol :
TNFRSF10D
details of functionality :
Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 30-60 ng/mL in the presence of 20 ng/mL of rhTRAIL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
633-TR
accessionNumbers :
Q9UBN6
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human TRAIL R4/TNFRSF10D protein Human TRAIL R4 (Ala56 - His211) Accession # Q9UBN6 IEGRID Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus
2020 USD :
359
2021 USD :
359 USD
alt names :
CD264, CD264 antigen, DcR2, DCR2decoy with truncated death domain, Decoy receptor 2, TNF receptor-related receptor for TRAIL, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4, TRAIL-R4, TRAILR4TRAIL receptor 4, TRUNDDTRAIL receptor with a truncated death domain, tumor necrosis factor receptor superfamily member 10D, tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.