Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF | R&D Systems 633-TR-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF

catalog :

633-TR-100

quantity :

100 ug

price :

456 USD

citations: 3

Reference
Tsai C, Sun D, Su M, Lien T, Chen Y, Lin C, et al. Suppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice. Sci Rep. 2020;10:6294 pubmed publisher
Lee Y, Hwang E, Jang Y. Involvement of p38 Activation and Mitochondria in Death of Human Leukemia Cells Induced by an Agonistic Human Monoclonal Antibody Fab Specific to TRAIL Receptor 1. Int J Mol Sci. 2019;20: pubmed publisher
Gasparian M, Chernyak B, Dolgikh D, Yagolovich A, Popova E, Sycheva A, et al. Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5. Apoptosis. 2009;14:778-87 pubmed publisher

product information

master code :

633-TR

SKU :

633-TR-100

product name :

Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TRAILR4/TNFRSF10D Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TRAILR4/TNFRSF10D

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

70-80 kDa, reducing conditions

theoretical molecular weight :

44.2 kDa (monomer)

gene symbol :

TNFRSF10D

details of functionality :

Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 6.00-60.0 ng/mL in the presence of 20 ng/mL of rhTRAIL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9UBN6

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human TRAILR4/TNFRSF10D protein Human TRAIL R4 (Ala56 - His211) Accession # Q9UBN6 IEGRID Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

CD264, CD264 antigen, DcR2, DCR2decoy with truncated death domain, Decoy receptor 2, TNF receptor-related receptor for TRAIL, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4, TRAIL-R4, TRAILR4TRAIL receptor 4, TRUNDDTRAIL receptor with a truncated death domain, tumor necrosis factor receptor superfamily member 10D, tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.