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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera, CF
catalog :
629-LR-100
quantity :
100 ug
price :
423 USD
more info or order :
citations: 5
Reference
Koh S, Kah J, Tham C, Yang N, Ceccarello E, Chia A, et al. Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3. Gastroenterology. 2018;155:180-193.e6 pubmed publisher
Dai X, Thiagarajan D, Fang J, Shen J, Annam N, Yang Z, et al. SM22? suppresses cytokine-induced inflammation and the transcription of NF-?B inducing kinase (Nik) by modulating SRF transcriptional activity in vascular smooth muscle cells. PLoS ONE. 2017;12:e0190191 pubmed publisher
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, et al. Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy. Biomaterials. 2010;31:3357-63 pubmed publisher
Dhawan P, Su Y, Thu Y, Yu Y, Baugher P, Ellis D, et al. The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells. J Biol Chem. 2008;283:15399-408 pubmed publisher
Edwards J, Sun S, Locklin R, Shipman C, Adamopoulos I, Athanasou N, et al. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum. 2006;54:1451-62 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
629-LR
SKU :
629-LR-100
product name :
Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera, CF
Description :
The Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera, CF has been validated for the following applications: Bioactivity not tested.
target :
Lymphotoxin beta R/TNFRSF3
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
70 kDa, reducing conditions
theoretical molecular weight :
49.6 kDa (monomer)
gene symbol :
LTBR
details of functionality :
Bioassay data are not available.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_002333
applications :
Bioactivity not tested
source :
NS0-derived Recombinant Human Lymphotoxin beta R (LTbR) Fc Chimera
USD :
423 USD
alt names :
CD18, D12S370, ltbetar, LT-BETA-R, LTBR, lymphotoxin B receptor, lymphotoxin beta receptor (TNFR superfamily, member 3), Lymphotoxin-beta receptor, LymphotoxinbR, TNF RIII, TNF Rrp, TNFCRTNF-RIII, TNFR superfamily, member 3, TNFR2-RP, TNFR3, TNF-R-III, TNFR-RP, TNFRSF3, TNFRSF3TNFR-III, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, tumor necrosis factor receptor superfamily member 3, tumor necrosis factor receptor superfamily, member 3, Tumor necrosis factor receptor type III
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.