Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF | R&D Systems 628-LK-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF

catalog :

628-LK-025/CF

quantity :

25 ug

price :

249 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, et al. Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma. Stem Cells. 2016;34:1112-22 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Jang S, Kim Y, Kim Y, Sung H, Ko J. Regulation of human LZIP expression by NF-kappaB and its involvement in monocyte cell migration induced by Lkn-1. J Biol Chem. 2007;282:11092-100 pubmed
Tian Y, New D, Yung L, Allen R, Slocombe P, Twomey B, et al. Differential chemokine activation of CC chemokine receptor 1-regulated pathways: ligand selective activation of Galpha 14-coupled pathways. Eur J Immunol. 2004;34:785-795 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

628-LK/CF

SKU :

628-LK-025/CF

product name :

Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF

Description :

The Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF from R&D Systems is derived from E. coli. The Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF has been validated for the following applications: Bioactivity.

target :

CCL15/MIP-1 delta

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

7.4 kDa

gene symbol :

CCL15

details of functionality :

Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 2-4 ng/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR1. The ED50 for this effect is 0.6-3 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q16663

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa)

USD :

249 USD

alt names :

chemokine (C-C motif) ligand 15, Chemokine CC-2, HCC-2, HCC-2Lkn-1, leukotactin 1, Leukotactin-1, LKN1, LKN-1, Macrophage inflammatory protein 5, MIP1 delta, MIP-1 delta, MIP5, MIP-5, MIP-5MIP-1d, Mrp-2b, NCC-3, NCC-3MIP-1D, NCC3MRP-2B, new CC chemokine 3, SCYA15member 15, Small-inducible cytokine A15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage