Recombinant Human CD6 Fc Chimera Protein, CF | R&D Systems 627-CD-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD6 Fc Chimera Protein, CF

catalog :

627-CD-100

quantity :

100 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Zhang L, Borjini N, Lun Y, Parab S, Asonye G, Singh R, et al. CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis. JCI Insight. 2022;7: pubmed publisher
Enyindah Asonye G, Li Y, Ruth J, Spassov D, Hebron K, Zijlstra A, et al. CD318 is a ligand for CD6. Proc Natl Acad Sci U S A. 2017;114:E6912-E6921 pubmed publisher
Te Riet J, Helenius J, Strohmeyer N, Cambi A, Figdor C, Muller D. Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6. J Cell Sci. 2014;127:1595-606 pubmed publisher
Tabata T, Petitt M, Fang Hoover J, Rivera J, Nozawa N, Shiboski S, et al. Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model. Am J Pathol. 2012;181:1540-59 pubmed publisher
Red Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, et al. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. J Clin Invest. 2006;116:2643-52 pubmed
Fischer M, Harvima I, Carvalho R, Möller C, Naukkarinen A, Enblad G, et al. Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion. J Clin Invest. 2006;116:2748-56 pubmed
Ibáñez A, Sarrias M, Farnós M, Gimferrer I, Serra Pagès C, Vives J, et al. Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface receptor. J Immunol. 2006;177:1152-9 pubmed
Zimmerman A, Joosten B, Torensma R, Parnes J, van Leeuwen F, Figdor C. Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood. 2006;107:3212-20 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

627-CD

SKU :

627-CD-100

product name :

Recombinant Human CD6 Fc Chimera Protein, CF

Description :

The Recombinant Human CD6 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD6 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD6

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

110 kDa, reducing conditions

theoretical molecular weight :

68.2 kDa (monomer)

gene symbol :

CD6

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of HuT 78 human cutaneous T cell lymphoma cells. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAA86417.1

applications :

Bioactivity

source :

NS0-derived Recombinant Human CD6 Fc Chimera Protein

USD :

423 USD

alt names :

CD6, CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage