Recombinant Human Hexosaminidase A/HEXA Protein, CF | R&D Systems 6237-GH-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Hexosaminidase A/HEXA Protein, CF

catalog :

6237-GH-020

quantity :

20 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Désiré J, Foucart Q, Poveda A, Gourlaouen G, Shimadate Y, Kise M, et al. Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif. Carbohydr Res. 2022;511:108491 pubmed publisher
Boado R, Lu J, Hui E, Lin H, Pardridge W. Bi-functional IgG-lysosomal enzyme fusion proteins for brain drug delivery. Sci Rep. 2019;9:18632 pubmed publisher
Njume F, Ghogomu S, Shey R, Gainkam L, Poelvoorde P, Humblet P, et al. Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein. PLoS Negl Trop Dis. 2019;13:e0007591 pubmed publisher
Thaysen Andersen M, Venkatakrishnan V, Loke I, Laurini C, Diestel S, Parker B, et al. Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum. J Biol Chem. 2015;290:8789-802 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

6237-GH

SKU :

6237-GH-020

product name :

Recombinant Human Hexosaminidase A/HEXA Protein, CF

description :

The Recombinant Human Hexosaminidase A/HEXA Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Hexosaminidase A/HEXA Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Hexosaminidase A/HEXA

unit size :

20 ug

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

observed molecular weight :

57-61 kDa, reducing conditions

theoretical molecular weight :

59 kDa

gene symbol :

HEXA

details of functionality :

Measured by its ability to hydrolyze 4-methylumbelliferyl-N-acetyl¿ß-D-glucosaminide (4-MU-GlcNAc) The specific activity is 1,250 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P06865

applications :

Enzyme Activity

product keywords :

6237-GH, rhHEXA, hHEXA, carrier-free, carrier free, 6237GH, bioprocessingenzymes, glycobiologyenzymes, HEX A, Glycosidase, Glycosidases, N-acetyl-beta-glucosaminidase, beta-N-acetylhexosaminidase, GM2 gangliosidosis type I, Tay-Sachs disease

source :

Sf 21 (baculovirus)-derived Recombinant Human Hexosaminidase A/HEXA Protein, CF

USD :

423

USD 2025 :

432 USD

alt names :

beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, EC 3.2.1, EC 3.2.1.52, HEXA, hexosaminidase A (alpha polypeptide), Hexosaminidase subunit A, MGC99608, N-acetyl-beta-glucosaminidase subunit alpha, TSD

more info or order :

R&D Systems product webpage