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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FGF-10 Protein
catalog :
6224-FG-025
quantity :
25 ug
price :
329 USD
more info or order :
citations: 28
Reference
Brownfield D, de Arce A, Ghelfi E, Gillich A, Desai T, Krasnow M. Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling. Nat Commun. 2022;13:7137 pubmed publisher
Kim H, Song B, Park S, Choi S, Moon H, Hwang K, et al. Ultraefficient extracellular vesicle-guided direct reprogramming of fibroblasts into functional cardiomyocytes. Sci Adv. 2022;8:eabj6621 pubmed publisher
Hosaka N, Kanda S, Shimono T, Nishiyama T. Induction of γδT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells. J Cell Mol Med. 2021;25:10604-10613 pubmed publisher
Tomita H, Tanaka K, Hirata A, Okada H, Imai H, Shirakami Y, et al. Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas. Cell Rep. 2021;34:108772 pubmed publisher
Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, et al. Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021;12:560 pubmed publisher
Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards C, Heaton B, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. 2020;27:890-904.e8 pubmed publisher
Kiyokawa Y, Sato M, Noguchi H, Inada E, Iwase Y, Kubota N, et al. Drug-Induced Naïve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic β-Cell Lineage. J Clin Med. 2020;9: pubmed publisher
Lloyd K, Parsons B, Burkitt M, Moore A, Papoutsopoulou S, Boyce M, et al. Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. Cell Mol Gastroenterol Hepatol. 2020;10:113-132 pubmed publisher
Momozane T, Fukui E, Funaki S, Fujii M, Kinehara Y, Ito E, et al. Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor. Stem Cells Int. 2019;2019:1271682 pubmed publisher
Guerriero I, De Angelis M, D Angelo F, Leveque R, Savignano E, Roberto L, et al. Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved. Int J Mol Sci. 2019;20: pubmed publisher
Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed publisher
Westphal S, Gantert T, Kless C, Hüttinger K, Klingenspor M, Fromme T. Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Sci Rep. 2019;9:8470 pubmed publisher
Miyagi Shiohira C, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Noguchi H. Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA. Sci Rep. 2018;8:12341 pubmed publisher
Zhong C, Chen Z, Luo X, Wang C, Jiang H, Shao J, et al. Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells. Int J Biochem Cell Biol. 2018;96:79-89 pubmed publisher
Scavuzzo M, Yang D, Borowiak M. Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells. Sci Rep. 2017;7:10810 pubmed publisher
Chatzeli L, Gaete M, Tucker A. Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development. Development. 2017;144:2294-2305 pubmed publisher
Cerdá Esteban N, Naumann H, Ruzittu S, Mah N, Pongrac I, Cozzitorto C, et al. Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2. Nat Commun. 2017;8:14127 pubmed publisher
McCracken K, Aihara E, Martin B, Crawford C, Broda T, Treguier J, et al. Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature. 2017;541:182-187 pubmed publisher
Saitoh I, Sato M, Soda M, Inada E, Iwase Y, Murakami T, et al. Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose. PLoS ONE. 2016;11:e0163580 pubmed publisher
Quantius J, Schmoldt C, Vazquez Armendariz A, Becker C, El Agha E, Wilhelm J, et al. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair. PLoS Pathog. 2016;12:e1005544 pubmed publisher
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Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, et al. 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline. PLoS ONE. 2015;10:e0130147 pubmed publisher
Yang Z, Balic A, Michon F, Juuri E, Thesleff I. Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem Cells. 2015;33:1670-81 pubmed publisher
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Rebustini I, Hayashi T, Reynolds A, Dillard M, Carpenter E, Hoffman M. miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis. Development. 2012;139:191-202 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
6224-FG
SKU :
6224-FG-025
product name :
Recombinant Mouse FGF-10 Protein
Description :
The Recombinant Mouse FGF-10 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse FGF-10 Protein has been validated for the following applications: Bioactivity.
target :
FGF-10
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
17 kDa, reducing conditions
theoretical molecular weight :
17.1 kDa
gene symbol :
Fgf10
details of functionality :
Measured in a cell proliferation assay using 4MBr-5 rhesus monkey epithelial cells. Rubin, J.S. et al . (1989) Proc. Natl. Acad. Sci. USA 86 :802. The ED50 for this effect is 20-120 ng/mL
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_032028.1
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse FGF-10 Protein
USD :
329 USD
alt names :
FGF10, FGF-10, fibroblast growth factor 10, Keratinocyte growth factor 2, KGF2, KGF-2, produced by fibroblasts of urinary bladder lamina propria
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.