Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF | R&D Systems 6220-CL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF

catalog :

6220-CL

quantity :

20 ug

price :

369 USD

citations: 4

Reference
Yetkin Arik B, Vogels I, Neyazi N, van Duinen V, Houtkooper R, Van Noorden C, et al. Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells. Sci Rep. 2019;9:10414 pubmed publisher
Chen Y, Huang W, Jiang W, Wu X, Ye B, Zhou X. HIV-1 Tat Regulates Occludin and A? Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway. Oxid Med Cell Longev. 2016;2016:4196572 pubmed publisher
Kim S, Lee H, Jung S, Kim S, Lee J, Nam S, et al. Role of secreted type I collagen derived from stromal cells in two breast cancer cell lines. Oncol Lett. 2014;8:507-512 pubmed
Itzhaki O, Greenberg E, Shalmon B, Kubi A, Treves A, Shapira Frommer R, et al. Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma. PLoS ONE. 2013;8:e57160 pubmed publisher

product information

brand :

R&D Systems

master code :

6220-CL

SKU :

6220-CL-020

product name :

Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF

description :

The Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Collagen I alpha 1

category :

Proteins and Enzymes

unit size :

20 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

79-83 kDa, 54-56 kDa, 35-36 kDa, reducing conditions

theoretical molecular weight :

65 kDa (full-length), 40 kDa, 28 kDa

gene symbol :

COL1A1

details of functionality :

Measured by the cleavage of its C-terminal propeptide by Recombinant Human BMP-1/PCP (Catalog # 1927-ZN ). 50% of full-length Pro-Collagen I alpha 1 is cleaved by Recombinant Human BMP-1/PCP (Catalog # 1927-ZN ), as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

6220-CL

accessionNumbers :

P02452

applications :

Enzyme Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human Collagen I alpha 1 protein Gln23-Lys277 + Gly1094-Leu1464, with an N-terminal 6-His tag.

2020 USD :

349

2021 USD :

369 USD

alt names :

Alpha-1 type I collagen, COL1A1, COL-IA1, Collagen 1, Collagen 1 alpha 1, collagen alpha 1 chain type I, collagen alpha-1(I) chain, collagen of skin, tendon and bone, alpha-1 chain, Collagen Type I Alpha 1 Chain, collagen, type I, alpha 1, Collagen1, Collagen-1, EDSARTH1, OI4, pro-alpha-1 collagen type 1, Type I Procollagen Alpha 1 Chain

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.