Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF | R&D Systems 6220-CL-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF

catalog :

6220-CL-020

quantity :

20 ug

price :

499 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Ramos M, Tian L, de Ruiter E, Song C, Paucarmayta A, Singh A, et al. Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction. elife. 2021;10: pubmed publisher
Gonzalez Porras M, Stojkova K, Vaicik M, Pelowe A, Goddi A, Carmona A, et al. Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity. Sci Rep. 2021;11:5442 pubmed publisher
Bluhmki T, Bitzer S, Gindele J, Schruf E, Kiechle T, Webster M, et al. Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model. Sci Rep. 2020;10:13022 pubmed publisher
Yetkin Arik B, Vogels I, Neyazi N, van Duinen V, Houtkooper R, Van Noorden C, et al. Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells. Sci Rep. 2019;9:10414 pubmed publisher
Chen Y, Huang W, Jiang W, Wu X, Ye B, Zhou X. HIV-1 Tat Regulates Occludin and A? Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway. Oxid Med Cell Longev. 2016;2016:4196572 pubmed publisher
Kim S, Lee H, Jung S, Kim S, Lee J, Nam S, et al. Role of secreted type I collagen derived from stromal cells in two breast cancer cell lines. Oncol Lett. 2014;8:507-512 pubmed
Itzhaki O, Greenberg E, Shalmon B, Kubi A, Treves A, Shapira Frommer R, et al. Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma. PLoS ONE. 2013;8:e57160 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

6220-CL

SKU :

6220-CL-020

product name :

Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF

Description :

The Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Collagen I alpha 1

category :

Proteins and Enzymes

unit size :

20 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

79-83 kDa, 54-56 kDa, 35-36 kDa, reducing conditions

theoretical molecular weight :

65 kDa (full-length), 40 kDa, 28 kDa

gene symbol :

COL1A1

details of functionality :

Measured by the cleavage of its C-terminal propeptide by Recombinant Human BMP-1/PCP (Catalog # 1927-ZN ). 50% of full-length Pro-Collagen I alpha 1 is cleaved by Recombinant Human BMP-1/PCP (Catalog # 1927-ZN ), as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P02452

applications :

Enzyme Activity

source :

CHO-derived Recombinant Human Pro-Collagen I alpha 1/COL1A1 Protein

USD :

499 USD

alt names :

Alpha-1 type I collagen, COL1A1, COL-IA1, Collagen 1, Collagen 1 alpha 1, collagen alpha 1 chain type I, collagen alpha-1(I) chain, collagen of skin, tendon and bone, alpha-1 chain, Collagen Type I Alpha 1 Chain, collagen, type I, alpha 1, Collagen1, Collagen-1, EDSARTH1, OI4, pro-alpha-1 collagen type 1, Type I Procollagen Alpha 1 Chain

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage