This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Tie-1 Fc Chimera Protein, CF
catalog :
619-TI-100
quantity :
100 ug
price :
456 USD
citations: 2
Reference
Koya Y, Nara H, Yagi S, Ueno C, Kamohara M. An engineered tetra-valent antibody fully activates the Tie2 receptor with comparable potency to its natural ligand angiopoietin-1. Sci Rep. 2021;11:14021 pubmed publisher
Saharinen P, Eklund L, Miettinen J, Wirkkala R, Anisimov A, Winderlich M, et al. Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat Cell Biol. 2008;10:527-37 pubmed publisher
product information
master code :
619-TI
SKU :
619-TI-100
product name :
Recombinant Human Tie-1 Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Human Tie-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Tie-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Tie-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
105-120 kDa, reducing conditions
theoretical molecular weight :
107 kDa (monomer)
gene symbol :
TIE1
details of functionality :
Bioassay data are not available.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P35590
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human Tie-1 protein Human Tie-1 (Ala22-Gln760) Accession # P35590 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
source short :
NS0
USD :
456 USD
alt names :
EC 2.7.10, EC 2.7.10.1, JTK14soluble TIE1 variant 3, receptor tyrosine kinase, soluble TIE1 variant 1, soluble TIE1 variant 2, soluble TIE1 variant 5, Tie1, TIEsoluble TIE1 variant 4, tyrosine kinase with immunoglobulin and epidermal growth factor homologydomains 1, tyrosine kinase with immunoglobulin-like and EGF-like domains 1, tyrosine-protein kinase receptor Tie-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.