Recombinant Mouse ENPP-2/Autotaxin Protein, CF | R&D Systems 6187-EN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ENPP-2/Autotaxin Protein, CF

catalog :

6187-EN-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Mardjuki R, Wang S, Carozza J, Zirak B, Subramanyam V, Abhiraman G, et al. Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint. Cell Rep. 2024;43:114209 pubmed publisher
Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, et al. The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage. Sci Rep. 2019;9:7414 pubmed publisher
Madan D, Ferguson C, Lee W, Prestwich G, Testa C. Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate. PLoS ONE. 2013;8:e79065 pubmed publisher

product information

master code :

6187-EN

SKU :

6187-EN-010

product name :

Recombinant Mouse ENPP-2/Autotaxin Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse ENPP-2/Autotaxin Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse ENPP-2/Autotaxin Protein, CF has been validated for the following applications: Enzyme Activity.

target :

ENPP-2/Autotaxin

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane.

species :

Mouse

observed molecular weight :

90-100 kDa, reducing conditions

theoretical molecular weight :

94 kDa

gene symbol :

Enpp2

details of functionality :

Measured by its ability to cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is 5,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9R1E6

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived mouse ENPP-2/Autotaxin protein Ser49-Ile862, with an N-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

ATX, ATXFLJ26803, ATX-X, AUTOTAXIN, autotaxin-t, EC 3.1.4.39, ectonucleotide pyrophosphatase/phosphodiesterase 2, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, ENPP2, Extracellular lysophospholipase D, Lysophosphatidic Acid, LysoPLD, NPP2, PD-IALPHA, PDNP2, PDNP2NPP2, phosphodiesterase I/nucleotide pyrophosphatase 2, plasma lysophospholipase D

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage