product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-8/CXCL8 (Endothelial Cell Derived), CF
catalog :
618-IL-010/CF
quantity :
10 ug (also 50 ug)
price :
181 USD
more info or order :
citations: 5
| Reference |
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Brown C, Vishwanath R, Aguilar B, Starr R, Najbauer J, Aboody K, et al. Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells. J Immunol. 2007;179:3332-41 pubmed
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Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. Int J Oncol. 2007;30:977-83 pubmed
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Fan X, Patera A, Pong Kennedy A, Deno G, Gonsiorek W, Manfra D, et al. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem. 2007;282:11658-66 pubmed
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Olivotto E, Vitellozzi R, Fernandez P, Falcieri E, Battistelli M, Burattini S, et al. Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B. J Cell Physiol. 2007;210:417-27 pubmed
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product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
618-IL/CF
SKU :
618-IL-010/CF
product name :
Recombinant Human IL-8/CXCL8 (Endothelial Cell Derived), CF
Description :
The Recombinant Human IL-8/CXCL8 (Endothelial Cell Derived), CF from R&D Systems is derived from E. coli. The Recombinant Human IL-8/CXCL8 (Endothelial Cell Derived), CF has been validated for the following applications: Bioactivity.
target :
IL-8/CXCL8
category :
Proteins and Enzymes
unit size :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
8.9 kDa
gene symbol :
CXCL8
details of functionality :
Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al . (1987) J. Immunol. 139 :3474. The ED50 for this effect is 0.2-0.4 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 1-5 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P10145
applications :
Bioactivity
source :
E. coli-derived Recombinant Human IL-8/CXCL8 (Endothelial Cell Derived)
USD :
181 USD
alt names :
3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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