product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ADAMTS13 (Full Length) Protein, CF
catalog :
6156-AD-020
quantity :
20 ug
price :
476 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Bi Y, Su J, Zhou S, Zhao Y, Zhang Y, Zhang H, et al. Distinct impact of IgG subclass on autoantibody pathogenicity in different IgG4-mediated diseases. elife. 2022;11: pubmed publisher
Ito T, Minamitani T, Hayakawa M, Otsubo R, Akiba H, Tsumoto K, et al. Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support. Sci Rep. 2021;11:22341 pubmed publisher
Kretz C, Tomberg K, Van Esbroeck A, Yee A, Ginsburg D. High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13. Sci Rep. 2018;8:2788 pubmed publisher
Lee M, Keener J, Xiao J, Long Zheng X, Rodgers G. ADAMTS13 and its variants promote angiogenesis via upregulation of VEGF and VEGFR2. Cell Mol Life Sci. 2015;72:349-56 pubmed publisher
Muroi C, Fujioka M, Mishima K, Irie K, Fujimura Y, Nakano T, et al. Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage. J Thromb Haemost. 2014;12:505-14 pubmed publisher
product information
brand :
R&D Systems
master code :
6156-AD
SKU :
6156-AD-020
product name :
Recombinant Human ADAMTS13 (Full Length) Protein, CF
description :
The Recombinant Human ADAMTS13 (Full Length) Protein, CF from R&D Systems is derived from CHO. The Recombinant Human ADAMTS13 (Full Length) Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ADAMTS13
category :
Proteins and Enzymes
sizes available :
20 ug
buffer :
Supplied as a 0.2 µm filtered solution in HEPES and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
160-180 kDa, reducing conditions
theoretical molecular weight :
147 kDa 151 kDa
gene symbol :
ADAMTS13
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate, FRETS-VWF73. The specific activity is 10 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q76LX8
applications :
Enzyme Activity
source :
CHO-derived Recombinant Human ADAMTS13 (Full Length) Protein, CF
USD :
453
USD 2023 :
476 USD
alt names :
A disintegrin and metalloproteinase with thrombospondin motifs 13, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 13, ADAM metallopeptidase with thrombospondin type 1 motif, 13, ADAM-TS13, ADAMTS-13, DKFZp434C2322, EC 3.4.24.14, EC 3.4.24.82, EC 3.4.24.87, FLJ42993, MGC118899, MGC118900, TTP, TTPADAM-TS 13, vWF-cleaving protease, vWF-CP, vWF-CPC9orf8, VWFCPvon Willebrand factor-cleaving protease
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.