Recombinant Human BMP-5 (CHO-expressed) Protein | R&D Systems 615-BMC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human BMP-5 (CHO-expressed) Protein

catalog :

615-BMC

quantity :

20 ug

price :

439 USD

citations: 7

Reference
Middleton L, Shen Z, Varma S, Pollack A, Gong X, Zhu S, et al. Genomic analysis of benign prostatic hyperplasia implicates cellular re-landscaping in disease pathogenesis. JCI Insight. 2019;5: pubmed publisher
Steinfeld J, Steinfeld I, Bausch A, Coronato N, Hampel M, Depner H, et al. BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling. Biol Open. 2017;6:979-992 pubmed publisher
Mann Z, Thiede B, Chang W, Shin J, May Simera H, Lovett M, et al. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun. 2014;5:3839 pubmed publisher
Lorda Diez C, Montero J, Choe S, Garcia Porrero J, Hurle J. Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro. J Bone Miner Res. 2014;29:735-48 pubmed publisher
Wu Q, Sun C, Lin H, Babitt J. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE. 2012;7:e46307 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher

product information

brand :

R&D Systems

master code :

615-BMC

SKU :

615-BMC-020

product name :

Recombinant Human BMP-5 (CHO-expressed) Protein

description :

The Recombinant Human BMP-5 (CHO-expressed) Protein from R&D Systems is derived from CHO. The Recombinant Human BMP-5 (CHO-expressed) Protein has been validated for the following applications: Bioactivity.

target :

BMP-5

category :

Proteins and Enzymes

unit size :

20 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

18-23 kDa, reducing conditions

theoretical molecular weight :

15.6 kDa

gene symbol :

BMP5

details of functionality :

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.2-1.2 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

615-BMC

accessionNumbers :

P22003

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human BMP-5 protein Ala317-His454

2020 USD :

439

2021 USD :

439 USD

alt names :

BMP5, BMP-5, bone morphogenetic protein 5, MGC34244

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.