Recombinant Human alpha-Galactosidase A/GLA Protein, CF | R&D Systems 6146-GH-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human alpha-Galactosidase A/GLA Protein, CF

catalog :

6146-GH-020

quantity :

20 ug

price :

394 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Cecioni S, Ashmus R, Gilormini P, Zhu S, Chen X, Shan X, et al. Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates. Nat Chem Biol. 2022;18:332-341 pubmed publisher
Besada P, Gallardo Gómez M, Pérez Márquez T, Patiño Álvarez L, Pantano S, Silva López C, et al. The New Pharmacological Chaperones PBXs Increase α-Galactosidase A Activity in Fabry Disease Cellular Models. Biomolecules. 2021;11: pubmed publisher

product information

brand :

R&D Systems

master code :

6146-GH

SKU :

6146-GH-020

product name :

Recombinant Human alpha-Galactosidase A/GLA Protein, CF

description :

The Recombinant Human alpha-Galactosidase A/GLA Protein, CF from R&D Systems is derived from CHO. The Recombinant Human alpha-Galactosidase A/GLA Protein, CF has been validated for the following applications: Enzyme Activity.

target :

alpha-Galactosidase A/GLA

category :

Proteins and Enzymes

sizes available :

20 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

45-55 kDa, reducing conditions

theoretical molecular weight :

46 kDa

gene symbol :

GLA

details of functionality :

Measured by its ability to hydrolyze 4-methylumbelliferyl-alpha-D-galactopyranoside. The specific activity is 1,100 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P06280

applications :

Enzyme Activity

source :

CHO-derived Recombinant Human alpha-Galactosidase A/GLA Protein, CF

USD :

388

USD 2023 :

394 USD

alt names :

Agalsidase, agalsidase alfa, Agalsidase alpha, Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, alpha-D-galactoside galactohydrolase 1, alpha-gal A, alpha-galactosidase A, EC 3.2.1, EC 3.2.1.22, GALA, galactosidase, alpha, melibiase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage