product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ENPP-1 Protein, CF
catalog :
6136-EN-010
quantity :
10 ug
price :
541 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Baird J, Alice A, Saito R, Chai Q, Han M, Ng C, et al. A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression. Sci Rep. 2024;14:29913 pubmed publisher
Hong C, Menshikova E, Whiteside T, Jackson E. Assessment of ATP Metabolism to Adenosine by Ecto-Nucleotidases Carried by Tumor-Derived Small Extracellular Vesicles. Res Sq. 2024;: pubmed publisher
Jekle A, Thatikonda S, Jaisinghani R, Ren S, Kinkade A, Stevens S, et al. Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models. Int J Mol Sci. 2023;24: pubmed publisher
Madan D, Ferguson C, Lee W, Prestwich G, Testa C. Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate. PLoS ONE. 2013;8:e79065 pubmed publisher
product information
master code :
6136-EN
SKU :
6136-EN-010
product name :
Recombinant Human ENPP-1 Protein, CF
unit size :
10 ug
description :
The Recombinant Human ENPP-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ENPP-1 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ENPP-1
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
100-135 kDa, reducing conditions
theoretical molecular weight :
96 kDa
gene symbol :
ENPP1
details of functionality :
Measured by its ability to hydrolyze thymidine 5'-monophosphate p-nitrophenyl ester. The specific activity is 35,000 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P22413 (ENPP-1) Q13822 (ENPP-2)
applications :
Enzyme Activity
source long :
Mouse myeloma cell line, NS0-derived human ENPP-1 protein. His ENPP-2 Asp49-Trp144 Accession # Q13822 ENPP-1 Val191-Leu591 Accession # P22413 ENPP-2 Asn532-Ile863 Accession # Q13822 N-terminus C-terminus
source short :
NS0
USD :
541 USD
alt names :
ectonucleotide pyrophosphatase/phosphodiesterase 1, E-NPP 1, ENPP1, Ly-41 Antigen, M6S1, M6S1NPP1, Membrane component chromosome 6 surface marker 1, membrane component, chromosome 6, surface marker 1, NPP1, NPPS, NPPSalkaline phosphodiesterase 1, PC1, PC-1, PCA1, PCA1ARHR2, PDNP1, PDNP1ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Phosphodiesterase I/nucleotide pyrophosphatase 1, plasma-cell membrane glycoprotein 1, Plasma-cell membrane glycoprotein PC-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.