product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human GFR alpha-2 Fc Chimera Protein, CF
catalog :
613-FR-100
quantity :
100 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher
Tatsumi N, Miki R, Katsu K, Yokouchi Y. Neurturin-GFRalpha2 signaling controls liver bud migration along the ductus venosus in the chick embryo. Dev Biol. 2007;307:14-28 pubmed
product information
master code :
613-FR
SKU :
613-FR-100
product name :
Recombinant Human GFR alpha-2 Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Human GFR alpha-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human GFR alpha-2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
GFR alpha-2/GDNF R alpha-2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
100 kDa, reducing conditions
theoretical molecular weight :
74 kDa (monomer)
gene symbol :
GFRA2
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Neurturin (Catalog # 1297-NE ) at 1 ╡g/mL can bind Recombinant Human GFR alpha -2/GDNF R alpha -2 Fc Chimera with an apparent KD 1 nM.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O00451
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived human GFR alpha-2/GDNF R alpha-2 protein Human GFR alpha -2 (Ser22-Ser441) Accession # O00451 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
GDNF family receptor alpha 2, GDNF family receptor alpha-2, GDNF R alpha-2, GDNF receptor alpha-2, GDNF receptor beta, GDNFR-alpha-2, GDNFR-beta, GDNFRBRET ligand 2, GFR alpha2, GFRa-2, GFRA2, GFR-alpha 2, GFR-alpha-2, glial cell line derived neurotrophic factor receptor, beta, Neurturin receptor alpha, NRTNR-alpha, NTNRA, NTNR-alpha, PI-linked cell-surface accessory protein, RETL2TGF-beta-related neurotrophic factor receptor 2, TGF-beta related neurotrophic factor receptor 2, TRN receptor, GPI-anchored, TRNR2NRTNR-ALPHA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.