Recombinant Mouse Fas Ligand/TNFSF6 Protein | R&D Systems 6128-SA-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Fas Ligand/TNFSF6 Protein

catalog :

6128-SA-025

quantity :

25 ug

price :

432 USD

citations: 4

Reference
May L, Hu B, Jerajani P, Jagdeesh A, Alhawiti O, Cai L, et al. The Innate Immune System and the TRAIL-Bcl-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females. Cancer Res. 2024;84:4140-4155 pubmed publisher
Cao L, Ma L, Zhao J, Wang X, Fang X, Li W, et al. An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo. elife. 2023;12: pubmed publisher
Wubben T, Chaudhury S, Watch B, Stuckey J, Weh E, Fernando R, et al. Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis. Pharmaceuticals (Basel). 2023;16: pubmed publisher
Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, et al. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation. J Biol Chem. 2014;289:11522-35 pubmed publisher

product information

master code :

6128-SA

SKU :

6128-SA-025

product name :

Recombinant Mouse Fas Ligand/TNFSF6 Protein

unit size :

25 ug

description :

The Recombinant Mouse Fas Ligand/TNFSF6 Protein from R&D Systems is derived from CHO. The Recombinant Mouse Fas Ligand/TNFSF6 Protein has been validated for the following applications: Bioactivity.

target :

Fas Ligand/TNFSF6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

40-55 kDa, reducing conditions

theoretical molecular weight :

25.9 kDa (monomer)

gene symbol :

Fasl

details of functionality :

Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is 1-8 ng/mL in the presence of 2.5 ╡g/mL of a cross-linking antibody, Mouse Anti-Hemagglutinin/HA Peptide Monoclonal Antibody (Catalog # MAB060 ).

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P41047

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse Fas Ligand/TNFSF6 protein Hemagglutinin Tag (YPYDVPDYA) GCN4-IZ (GGGS)3 Mouse Fas Ligand (Gln101-Leu279) Accession # P41047 N-terminus C-terminus

source short :

CHO

USD :

432 USD

alt names :

apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.