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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF
catalog :
6128-SA-025/CF
quantity :
25 ug
price :
394 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, et al. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation. J Biol Chem. 2014;289:11522-35 pubmed publisher
product information
brand :
R&D Systems
master code :
6128-SA/CF
SKU :
6128-SA-025/CF
product name :
Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF
description :
The Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF has been validated for the following applications: Bioactivity.
target :
Fas Ligand/TNFSF6
category :
Proteins and Enzymes
sizes available :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
40-55 kDa, reducing conditions
theoretical molecular weight :
25.9 kDa (monomer)
gene symbol :
Fasl
details of functionality :
Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is 1-8 ng/mL in the presence of 2.5 µg/mL of a cross-linking antibody, Mouse Anti-Hemagglutinin/HA Peptide Monoclonal Antibody (Catalog # MAB060 ).
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P41047
applications :
Bioactivity
source :
CHO-derived Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF
USD :
388
USD 2023 :
394 USD
alt names :
apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.