product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CD44 Fc Chimera Protein, CF
catalog :
6127-CD-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Van Dinther M, Cunningham K, Singh S, White M, Campion T, Ciancia C, et al. CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proc Natl Acad Sci U S A. 2023;120:e2302370120 pubmed publisher
Kellett Clarke H, Stegmann M, Barclay A, Metcalfe C. CD44 Binding to Hyaluronic Acid Is Redox Regulated by a Labile Disulfide Bond in the Hyaluronic Acid Binding Site. PLoS ONE. 2015;10:e0138137 pubmed publisher
product information
master code :
6127-CD
SKU :
6127-CD-050
product name :
Recombinant Mouse CD44 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse CD44 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse CD44 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD44
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
70-95 kDa, reducing conditions
theoretical molecular weight :
49.3 kDa (monomer)
gene symbol :
Cd44
details of functionality :
Measured by its binding ability in a functional ELISA. When rmCD44 Fc Chimera is present at 1 ╡g/mL, the concentration of biotinylated hyaluronan that produces 50% of the optimal binding response is found to be approximately 15-60 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_033981
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived mouse CD44 protein Mouse CD44 (Gln25 - Thr224) Accession # NP_033981 IEGRMDP Mouse IgG2A (Glu98 - Lys330) N-terminus C-terminus
source short :
CHO
USD :
432 USD
alt names :
CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.