Recombinant Human Cardiotrophin-1/CT-1 Protein, CF | R&D Systems 612-CD-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cardiotrophin-1/CT-1 Protein, CF

catalog :

612-CD-010/CF

quantity :

10 ug (also 50 ug)

price :

355 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Lindkvist M, Zegeye M, Greneg xe5 rd M, Ljungberg L. Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. Int J Mol Sci. 2022;23: pubmed publisher
Martínez Martínez E, Ibarrola J, Fernández Celis A, Santamaria E, Fernández Irigoyen J, Rossignol P, et al. Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts. Sci Rep. 2017;7:12192 pubmed publisher
Emdad L, D Souza S, Kothari H, Qadeer Z, Germano I. Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes. Stem Cells Dev. 2012;21:404-10 pubmed publisher
Larsen J, Hansen M, Møller B, Madsen P, Scheller J, Nielsen M, et al. Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer. Mol Cell Biol. 2010;30:4175-87 pubmed publisher
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher
Fritzenwanger M, Meusel K, Foerster M, Kuethe F, Krack A, Figulla H. Cardiotrophin-1 induces interleukin-6 synthesis in human monocytes. Cytokine. 2007;38:137-44 pubmed
Gard A, Gavin E, Solodushko V, Pennica D. Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system. Neuroscience. 2004;127:43-52 pubmed
Freed D, Borowiec A, Angelovska T, Dixon I. Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways. Cardiovasc Res. 2003;60:365-75 pubmed

product information

master code :

612-CD/CF

SKU :

612-CD-010/CF

product name :

Recombinant Human Cardiotrophin-1/CT-1 Protein, CF

unit size :

10 ug (also 50 ug)

description :

The Recombinant Human Cardiotrophin-1/CT-1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Cardiotrophin-1/CT-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Cardiotrophin-1/CT-1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

21 kDa

gene symbol :

CTF1

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.25-1.25 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q16619

applications :

Bioactivity

source long :

E. coli -derived human Cardiotrophin-1/CT-1 protein Ser2-Ala201

source short :

E. coli

USD :

355 USD

alt names :

cardiophin 1, cardiotrophin 1, cardiotrophin-1, Cardiotrophin1, CT-1CT1, CTF1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage