Wnt-4 Protein | R&D Systems 6076-WN-005/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Wnt-4 Protein

catalog :

6076-WN-005/CF

quantity :

5 ug

price :

409 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Yucer N, Holzapfel M, Jenkins Vogel T, Lenaeus L, Ornelas L, Laury A, et al. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium. Sci Rep. 2017;7:10741 pubmed publisher
Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni S, et al. Identification of proliferative and mature ?-cells in the islets of Langerhans. Nature. 2016;535:430-4 pubmed
Kilander M, Dahlström J, Schulte G. Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling and reveals WNT-Frizzled selectivity. Cell Signal. 2014;26:1943-9 pubmed publisher
Garcia Castro B, Alvarez Zavala M, Riveros Magaña A, Ortiz Lazareno P, Ratkovich González S, Hernandez Flores G, et al. Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines. BMC Cancer. 2013;13:557 pubmed publisher
Thrasivoulou C, Millar M, Ahmed A. Activation of intracellular calcium by multiple Wnt ligands and translocation of ?-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/?-catenin pathways. J Biol Chem. 2013;288:35651-9 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher

product information

brand :

R&D Systems

SKU :

6076-WN-005/CF

product name :

Wnt-4 Protein

unit sizes :

5 ug

description :

The Recombinant Human Wnt-4 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Wnt-4 Protein, CF has been validated for the following applications: Bioactivity.

target :

Wnt-4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and CHAPS.

conjugate :

Unconjugated

purity :

>60%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

42-80 kDa, reducing conditions

theoretical molecular weight :

39.1 kDa

gene symbol :

WNT4

details of functionality :

Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The typical ED50 for this effect is 20-100 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

6076-WN/CF

accessionNumbers :

P56705

applications :

Bioactivity

source :

The Recombinant Human Wnt-4 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Wnt-4 Protein, CF has been validated for the following applications: Bioactivity.

USD :

409 USD

applications abr :

alt names :

protein Wnt-4, SERKAL, wingless-type MMTV integration site family, member 4, Wnt4, WNT-4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage