Goswami Y, Baghel A, Sharma G, Sharma P, Biswas S, Yadav R, et al. Liver Organoids From Hepatocytes of Healthy Humans and Non-alcoholic Fatty Liver Disease (NAFLD) Patients Display Multilineage Architecture and can be Used to Develop an In Vitro Model of Steatohepatitis. J Clin Exp Hepatol. 2025;15:102463 pubmed publisher

Balogh A, B xf3 di Jakus M, Karl V, Bell xe1 k T, Sz xe9 ky B, Farkas J, et al. Establishment of human pluripotent stem cell-derived cortical neurosphere model to study pathomechanisms and chemical toxicity in Kleefstra syndrome. Sci Rep. 2024;14:22572 pubmed publisher

Wang X, Yang S, Zheng C, Huang C, Yao H, Guo Z, et al. Multi-Omics Profiles of Small Intestine Organoids in Reaction to Breast Milk and Different Infant Formula Preparations. Nutrients. 2024;16: pubmed publisher

Lekkala V, Shrestha S, Qaryoute A, Dhinoja S, Acharya P, Raheem A, et al. Enhanced Maturity and Functionality of Vascularized Human Liver Organoids through 3D Bioprinting and Pillar Plate Culture. bioRxiv. 2024;: pubmed publisher

Basu B, Karwatka M, China B, McKibbin M, Khan K, Inglehearn C, et al. Glycogen myophosphorylase loss causes increased dependence on glucose in iPSC-derived retinal pigment epithelium. J Biol Chem. 2024;300:107569 pubmed publisher

Cao L, Lin G, Fan D, Weng K, Chen Y, Wang J, et al. NUAK1 activates STAT5/GLI1/SOX2 signaling to enhance cancer cell expansion and drives chemoresistance in gastric cancer. Cell Rep. 2024;43:114446 pubmed publisher

Vihma H, Li K, Welton Arndt A, Smith A, Bettadapur K, Gilmore R, et al. Ube3a unsilencer for the potential treatment of Angelman syndrome. Nat Commun. 2024;15:5558 pubmed publisher

Chien Y, Huang X, Yarmishyn A, Chien C, Liu Y, Hsiao Y, et al. Paracrinal regulation of neutrophil functions by coronaviral infection in iPSC-derived alveolar type II epithelial cells. Virus Res. 2024;345:199391 pubmed publisher

Jang K, Ercelen D, Cen Feng J, Gurunathan S, Zhou C, Korman A, et al. Tofacitinib uptake by patient-derived intestinal organoids predicts individual clinical responsiveness. bioRxiv. 2024;: pubmed publisher

Kang E, Kim J, Kim Y, Lee H, Jung K, Chang D, et al. The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation. Nat Commun. 2024;15:2983 pubmed publisher

Qu N, Daoud A, Kechele D, M xfa nera J. Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut. bioRxiv. 2024;: pubmed publisher

Wang M, Zhang L, Novak S, Yu J, Gallina I, Xu L, et al. Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nat Biotechnol. 2024;: pubmed publisher

Kwon O, Lee H, Jung J, Son Y, Jeon S, Yoo W, et al. Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids. Nat Commun. 2024;15:799 pubmed publisher

Kuroda T, Yasuda S, Matsuyama S, Miura T, Sawada R, Matsuyama A, et al. ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons. Sci Rep. 2024;14:690 pubmed publisher

Reumann D, Krauditsch C, Novatchkova M, Sozzi E, Wong S, Zabolocki M, et al. In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids. Nat Methods. 2023;20:2034-2047 pubmed publisher

M xfa nera J, Kechele D, Bouffi C, Qu N, Jing R, Maity P, et al. Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon. Cell Stem Cell. 2023;30:1434-1451.e9 pubmed publisher

Menjivar N, Gad A, Thompson R, Meyers M, Hollinshead F, Tesfaye D. Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress. BMC Genomics. 2023;24:646 pubmed publisher

Sutton K, Nash T, Sives S, Borowska D, MITCHELL J, Vohra P, et al. Disentangling the innate immune responses of intestinal epithelial cells and lamina propria cells to Salmonella Typhimurium infection in chickens. Front Microbiol. 2023;14:1258796 pubmed publisher

Hsu W, LaBella K, Lin Y, Xu P, Lee R, Hsieh C, et al. Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression. Cancer Discov. 2023;13:2652-2673 pubmed publisher

Lass xe9 M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, et al. An integrated organoid omics map extends modeling potential of kidney disease. Nat Commun. 2023;14:4903 pubmed publisher

Mubariz F, Saadin A, Lingenfelter N, Sarkar C, Banerjee A, Lipinski M, et al. Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson's disease. Front Neurosci. 2023;17:1152503 pubmed publisher

Choi S, van Unen V, Zhang H, Rustagi A, Alwahabi S, Santos A, et al. Organoid modeling of lung-resident immune responses to SARS-CoV-2 infection. Res Sq. 2023;: pubmed publisher

Yamakawa K, Koyanagi Aoi M, Machinaga A, Kakiuchi N, Hirano T, Kodama Y, et al. Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase. Cancer Cell Int. 2023;23:94 pubmed publisher

Darwish N, Hussein K, Elmasry K, Ibrahim A, Humble J, Moustafa M, et al. Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy. Cells. 2023;12: pubmed publisher

Matkovic Leko I, Schneider R, Thimraj T, Schrode N, Beitler D, Liu H, et al. A distal lung organoid model to study interstitial lung disease, viral infection and human lung development. Nat Protoc. 2023;18:2283-2312 pubmed publisher

Huang X, Nero T, Weerasekera R, Matej K, Hinbest A, Jiang Z, et al. Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization. Nat Commun. 2023;14:2104 pubmed publisher

Ghobashi A, Vuong T, Kimani J, O Hagan H. Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer. bioRxiv. 2023;: pubmed publisher

Tian J, Chen J, Chao S, Pelka K, Giannakis M, Hess J, et al. Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial. Nat Med. 2023;29:458-466 pubmed publisher

Kakni P, Jutten B, Teixeira Oliveira Carvalho D, Penders J, Truckenm xfc ller R, Habibovic P, et al. Hypoxia-tolerant apical-out intestinal organoids to model host-microbiome interactions. J Tissue Eng. 2023;14:20417314221149208 pubmed publisher

Madrigal P, Deng S, Feng Y, Militi S, Goh K, Nibhani R, et al. Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation. Nat Commun. 2023;14:405 pubmed publisher

Wong Y, Kumar Y, Proks M, Herrera J, Rothov xe1 M, Monteiro R, et al. Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation. Nat Cell Biol. 2023;25:481-492 pubmed publisher

Sun Y, Revach O, Anderson S, Kessler E, Wolfe C, Jenney A, et al. Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature. 2023;: pubmed publisher

Stevens A, Harris A, Gerdts J, Kim K, Trentesaux C, Ramirez J, et al. Programming multicellular assembly with synthetic cell adhesion molecules. Nature. 2023;614:144-152 pubmed publisher

Thompson R, Meyers M, Premanandan C, Hollinshead F. Generation and cryopreservation of feline oviductal organoids. Theriogenology. 2023;196:167-173 pubmed publisher

Ng E, Kady N, Hu J, Dave A, Jiang Z, Pei J, et al. Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration. Cells. 2022;11: pubmed publisher

Johnson K, Freedman S, Braun R, LaBonne C. Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions. BMC Genomics. 2022;23:723 pubmed publisher

Iannielli A, Luoni M, Giannelli S, Ferese R, Ordazzo G, Fossati M, et al. Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications. Cell Death Dis. 2022;13:881 pubmed publisher

Marei H, Tsai W, Kee Y, Ruiz K, He J, Cox C, et al. Antibody targeting of E3 ubiquitin ligases for receptor degradation. Nature. 2022;610:182-189 pubmed publisher

Kishimoto K, Iwasawa K, Sorel A, Ferran Heredia C, Han L, Morimoto M, et al. Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Nat Protoc. 2022;17:2699-2719 pubmed publisher

Kuwahara M, Akasaki Y, Goto N, Kurakazu I, Sueishi T, Toya M, et al. Fluvastatin promotes chondrogenic differentiation of adipose-derived mesenchymal stem cells by inducing bone morphogenetic protein 2. BMC Pharmacol Toxicol. 2022;23:61 pubmed publisher

Akrioti E, Karamitros T, Gkaravelas P, Kouroupi G, Matsas R, Taoufik E. Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson's Disease. Biomolecules. 2022;12: pubmed publisher

Ng K, Lim J, Tan Y, Quek D, Lim Z, Pantelireis N, et al. Sox2 in the dermal papilla regulates hair follicle pigmentation. Cell Rep. 2022;40:111100 pubmed publisher

Thompson R, Meyers M, Veeramachaneni D, Pukazhenthi B, Hollinshead F. Equine Oviductal Organoid Generation and Cryopreservation. Methods Protoc. 2022;5: pubmed publisher

Ohgushi M, Taniyama N, Vandenbon A, Eiraku M. Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model. Cell Rep. 2022;39:110973 pubmed publisher

Go Y, Choi W, Bae W, Jung S, Cho C, Lee S, et al. Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts. Cancers (Basel). 2022;14: pubmed publisher

Ding S, Hsu C, Wang Z, Natesh N, Millen R, Negrete M, et al. Patient-derived micro-organospheres enable clinical precision oncology. Cell Stem Cell. 2022;29:905-917.e6 pubmed publisher

Su xe1 rez Rivero J, Pastor Maldonado C, Romero Gonz xe1 lez A, G xf3 mez Fernandez D, Povea Cabello S, xc1 lvarez C xf3 rdoba M, et al. Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases. Front Pharmacol. 2022;13:862085 pubmed publisher

Kim S, Min S, Choi Y, Jo S, Jung J, Han K, et al. Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids. Nat Commun. 2022;13:1692 pubmed publisher

Zhou J, He H, Zhang J, Liu X, Yao W, Li C, et al. ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation. Autophagy. 2022;:1-23 pubmed publisher

Uehara K, Koyanagi Aoi M, Koide T, Itoh T, Aoi T. Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids. Stem Cell Reports. 2022;17:820-834 pubmed publisher

Zhao K, Shi Y, Yu J, Yu L, Mael A, Li Y, et al. Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells. Cell Transplant. 2022;31:9636897211066508 pubmed publisher

Vachenc S, Gobbo J, Moujarrebe S, Desmoulins I, Gilabert M, Beau Faller M, et al. OncoSNIPE® Study Protocol, a study of molecular profiles associated with development of resistance in solid cancer patients. BMC Cancer. 2022;22:41 pubmed publisher

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2022;16:101315 pubmed publisher

Eicher A, Kechele D, Sundaram N, Berns H, Poling H, Haines L, et al. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. 2022;29:36-51.e6 pubmed publisher

Yucer N, Ahdoot R, Workman M, Laperle A, Recouvreux M, Kurowski K, et al. Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis. Cell Rep. 2021;37:110146 pubmed publisher

Bruzelius A, Kidnapillai S, Drouin Ouellet J, Stoker T, Barker R, Rylander Ottosson D. Reprogramming Human Adult Fibroblasts into GABAergic Interneurons. Cells. 2021;10: pubmed publisher

Sharma R, George A, Nimmagadda M, Ortolan D, Karla B, Qureshy Z, et al. Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model. Nat Commun. 2021;12:7293 pubmed publisher

Chesnokova V, Zonis S, Apostolou A, Estrada H, Knott S, Wawrowsky K, et al. Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage. Cell Rep. 2021;37:110068 pubmed publisher

Orr B, Sutton K, Christian S, Nash T, Niemann H, Hansen L, et al. Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer. Vet Res. 2021;52:142 pubmed publisher

Robbins M, Pisupati V, Azzarelli R, Nehme S, Barker R, Fruk L, et al. Biofunctionalised bacterial cellulose scaffold supports the patterning and expansion of human embryonic stem cell-derived dopaminergic progenitor cells. Stem Cell Res Ther. 2021;12:574 pubmed publisher

Bai T, Peng C, Aneas I, Sakabe N, Requena D, Billstrand C, et al. Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts. Stem Cell Res. 2021;56:102507 pubmed publisher

Hellman S. Generation of equine enteroids and enteroid-derived 2D monolayers that are responsive to microbial mimics. Vet Res. 2021;52:108 pubmed publisher

Ali M, Khan S, Gottsch J, Hutchinson E, Khan A, Riazuddin S. Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty. Stem Cell Reports. 2021;16:2320-2335 pubmed publisher

Larsen B, Kannan M, Langer L, Leibowitz B, BenTaieb A, Cancino A, et al. A pan-cancer organoid platform for precision medicine. Cell Rep. 2021;36:109429 pubmed publisher

Vermeire B, Gonzalez L, Jansens R, Cox E, Devriendt B. Porcine small intestinal organoids as a model to explore ETEC-host interactions in the gut. Vet Res. 2021;52:94 pubmed publisher

Djidrovski I, Georgiou M, Hughes G, Patterson E, Casas Sánchez A, Pennington S, et al. SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells. Stem Cells. 2021;39:1310-1321 pubmed publisher

Hoare O, Fraunhoffer N, Elkaoutari A, Gayet O, Bigonnet M, Roques J, et al. Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models. Cancers (Basel). 2021;13: pubmed publisher

Nakashima H, Tsujimura K, Irie K, Imamura T, Trujillo C, Ishizu M, et al. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling. Cell Rep. 2021;35:109124 pubmed publisher

Norman M, Ferreira S, Jowett G, Bozec L, Gentleman E. Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy. Nat Protoc. 2021;16:2418-2449 pubmed publisher

Brookhouser N, Raman S, Frisch C, Srinivasan G, Brafman D. APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease. Mol Psychiatry. 2021;: pubmed publisher

Haellman V, Saxena P, Jiang Y, Fussenegger M. Rational design and optimization of synthetic gene switches for controlling cell-fate decisions in pluripotent stem cells. Metab Eng. 2021;65:99-110 pubmed publisher

Husain K, Coppola D, Yang C, Malafa M. Farnesyl dimethyl chromanol targets colon cancer stem cells and prevents colorectal cancer metastasis. Sci Rep. 2021;11:2185 pubmed publisher

Merlevede A, Legault E, Drugge V, Barker R, Drouin Ouellet J, Olariu V. A quantitative model of cellular decision making in direct neuronal reprogramming. Sci Rep. 2021;11:1514 pubmed publisher

Sarvestani S, SIGNS S, Hu B, Yeu Y, Feng H, Ni Y, et al. Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity. Nat Commun. 2021;12:262 pubmed publisher

Workman M, Troisi E, Targan S, Svendsen C, Barrett R. Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids. Int J Mol Sci. 2020;22: pubmed publisher

Forostyak S, Forostyak O, Kwok J, Romanyuk N, Rehorova M, Kriška J, et al. Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats. Int J Mol Sci. 2020;21: pubmed publisher

Zheng Y, Shao Y, Fu J. A microfluidics-based stem cell model of early post-implantation human development. Nat Protoc. 2021;16:309-326 pubmed publisher

Meisig J, Dreser N, Kapitza M, Henry M, Rotshteyn T, Rahnenführer J, et al. Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation. Nucleic Acids Res. 2020;48:12577-12592 pubmed publisher

Caldwell A, Liu Q, Schroth G, Galasko D, Yuan S, Wagner S, et al. Dedifferentiation and neuronal repression define familial Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher

Giacomoni J, Bruzelius A, Stamouli C, Rylander Ottosson D. Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons. Cells. 2020;9: pubmed publisher

Di Grazia A, Marafini I, Pedini G, Di Fusco D, Laudisi F, Dinallo V, et al. The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis. Cell Mol Gastroenterol Hepatol. 2021;11:639-658 pubmed publisher

Nolbrant S, Giacomoni J, Hoban D, Bruzelius A, Birtele M, Chandler Militello D, et al. Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons. Stem Cell Reports. 2020;15:869-882 pubmed publisher

Lloyd K, Papoutsopoulou S, Smith E, Stegmaier P, Bergey F, Morris L, et al. Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease. Dis Model Mech. 2020;13: pubmed publisher

Han L, Chaturvedi P, Kishimoto K, Koike H, Nasr T, Iwasawa K, et al. Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nat Commun. 2020;11:4158 pubmed publisher

Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed publisher

Teotia P, Niu M, Ahmad I. Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single-cell transcriptome analysis. Stem Cells. 2020;38:1279-1291 pubmed publisher

Kumar Gupta A, Sarkar P, Wertheim J, Pan X, Carroll T, Oxburgh L. Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids. Commun Biol. 2020;3:231 pubmed publisher

Vinckier N, Patel N, Geusz R, Wang A, Wang J, Matta I, et al. LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. Nat Commun. 2020;11:2082 pubmed publisher

Gunne Braden A, Sullivan A, Gharibi B, Sheriff R, Maity A, Wang Y, et al. GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells. Cell Stem Cell. 2020;26:693-706.e9 pubmed publisher

Yoshida S, Miwa H, Kawachi T, Kume S, Takahashi K. Generation of intestinal organoids derived from human pluripotent stem cells for drug testing. Sci Rep. 2020;10:5989 pubmed publisher

Liu Y, Michalska A, Dottori M, Eaton E, Courtney J, Antonic A, et al. Differential susceptibility of human neural progenitors and neurons to ischaemic injury. Brain Res Bull. 2020;156:25-32 pubmed publisher

Hyakumura T, McDougall S, Finch S, Needham K, Dottori M, Nayagam B. Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices. Stem Cells Int. 2019;2019:8419493 pubmed publisher

Piccand J, Vagne C, Blot F, Meunier A, Beucher A, Strasser P, et al. Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production. Mol Metab. 2019;29:24-39 pubmed publisher

Liang W, Han P, Kim E, Mak J, Zhang R, Torrente A, et al. Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells. Stem Cells. 2020;38:352-368 pubmed publisher

Tripathi A, Volsko C, Garcia J, Agirre E, Allan K, Tesar P, et al. Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination. Cell Rep. 2019;29:904-919.e9 pubmed publisher

Omi M, Kaartinen V, Mishina Y. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway. J Biol Chem. 2019;294:17818-17836 pubmed publisher

Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed publisher

Sachdeva R, Wu M, Johnson K, Kim H, Celebre A, Shahzad U, et al. BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma. Sci Rep. 2019;9:14569 pubmed publisher

Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher

Lungová V, Chen X, Wang Z, Kendziorski C, Thibeault S. Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure. Nat Commun. 2019;10:4161 pubmed publisher

Zheng Y, Xue X, Shao Y, Wang S, Esfahani S, Li Z, et al. Controlled modelling of human epiblast and amnion development using stem cells. Nature. 2019;573:421-425 pubmed publisher

Shik Mun K, Arora K, Huang Y, Yang F, Yarlagadda S, Ramananda Y, et al. Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders. Nat Commun. 2019;10:3124 pubmed publisher

Jung K, Kwon O, Lee M, Lee H, Son Y, Habib O, et al. Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells. J Clin Med. 2019;8: pubmed publisher

Ahlfors J, Azimi A, El Ayoubi R, Velumian A, Vonderwalde I, Boscher C, et al. Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells. Stem Cell Res Ther. 2019;10:166 pubmed publisher

Markouli C, De Deckersberg E, Regin M, Nguyen H, Zambelli F, Keller A, et al. Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment. Stem Cell Reports. 2019;: pubmed publisher

Marshall A, Luo W, Wang X, Lin T, Cai Y, Guzman R. Medial artery calcification increases neointimal hyperplasia after balloon injury. Sci Rep. 2019;9:8193 pubmed publisher

Blázquez Medela A, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, et al. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019;25:50-63 pubmed publisher

Wang X, Sterr M, Ansarullah -, Burtscher I, Böttcher A, Beckenbauer J, et al. Point mutations in the PDX1 transactivation domain impair human β-cell development and function. Mol Metab. 2019;24:80-97 pubmed publisher

Iwashita M, Ohta H, Fujisawa T, Cho M, Ikeya M, Kidoaki S, et al. Brain-stiffness-mimicking tilapia collagen gel promotes the induction of dorsal cortical neurons from human pluripotent stem cells. Sci Rep. 2019;9:3068 pubmed publisher

Chesnokova V, Zonis S, Barrett R, Kameda H, Wawrowsky K, Ben Shlomo A, et al. Excess growth hormone suppresses DNA damage repair in epithelial cells. JCI Insight. 2019;4: pubmed publisher

Miller A, Dye B, Ferrer Torres D, Hill D, Overeem A, Shea L, et al. Generation of lung organoids from human pluripotent stem cells in vitro. Nat Protoc. 2019;14:518-540 pubmed publisher

Ruzicka J, Romanyuk N, Jiráková K, Hejcl A, Janouskova O, Machova L, et al. The Effect of iPS-Derived Neural Progenitors Seeded on Laminin-Coated pHEMA-MOETACl Hydrogel with Dual Porosity in a Rat Model of Chronic Spinal Cord Injury. Cell Transplant. 2019;28:400-412 pubmed publisher

Field A, Jacobs F, Fiddes I, Phillips A, Reyes Ortiz A, LaMontagne E, et al. Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. Stem Cell Reports. 2019;12:245-257 pubmed publisher

Bradford S, Ranghini E, Grimley E, Lee P, Dressler G. High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds. J Biol Chem. 2019;294:3125-3136 pubmed publisher

Scavuzzo M, Chmielowiec J, Yang D, Wamble K, Chaboub L, Duraine L, et al. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Rep. 2018;25:3811-3827.e7 pubmed publisher

Bonamy C, Sechet E, Amiot A, Alam A, Mourez M, Fraisse L, et al. Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells. Sci Rep. 2018;8:18043 pubmed publisher

Li J, Narayanan C, Bian J, Sambo D, Brickler T, Zhang W, et al. A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family. PLoS ONE. 2018;13:e0208110 pubmed publisher

Broda T, McCracken K, Wells J. Generation of human antral and fundic gastric organoids from pluripotent stem cells. Nat Protoc. 2019;14:28-50 pubmed publisher

Bayo Puxan N, Terrasso A, Creyssels S, Simão D, Begon Pescia C, Lavigne M, et al. Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons. Sci Rep. 2018;8:16644 pubmed publisher

Buskin A, Zhu L, Chichagova V, Basu B, Mozaffari Jovin S, Dolan D, et al. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nat Commun. 2018;9:4234 pubmed publisher

Sechet E, Telford E, Bonamy C, Sansonetti P, Sperandio B. Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. Proc Natl Acad Sci U S A. 2018;115:E9869-E9878 pubmed publisher

Zhang Y, Yang Y, Jiang M, Huang S, Zhang W, Al Alam D, et al. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling. Cell Stem Cell. 2018;23:516-529.e5 pubmed publisher

Cruz Acuña R, Quirós M, Huang S, Siuda D, Spence J, Nusrat A, et al. PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery. Nat Protoc. 2018;13:2102-2119 pubmed publisher

Scavuzzo M, Hill M, Chmielowiec J, Yang D, Teaw J, Sheng K, et al. Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018;9:3356 pubmed publisher

Blair J, Hockemeyer D, Bateup H. Genetically engineered human cortical spheroid models of tuberous sclerosis. Nat Med. 2018;24:1568-1578 pubmed publisher

Haider S, Meinhardt G, Saleh L, Kunihs V, Gamperl M, Kaindl U, et al. Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta. Stem Cell Reports. 2018;11:537-551 pubmed publisher

Liu Y, Antonic A, Yang X, Korte N, Lim K, Michalska A, et al. Derivation of phenotypically diverse neural culture from hESC by combining adherent and dissociation methods. J Neurosci Methods. 2018;308:286-293 pubmed publisher

Chen S, Jia L, Zhang S, Zheng Y, Zhou Y. DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis. Stem Cell Res Ther. 2018;9:185 pubmed publisher

Tan K, Lim W, Chai C, Kukumberg M, Lim K, Goh E, et al. Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. Sci Rep. 2018;8:9567 pubmed publisher

Workman M, Gleeson J, Troisi E, Estrada H, Kerns S, HINOJOSA C, et al. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips. Cell Mol Gastroenterol Hepatol. 2018;5:669-677.e2 pubmed publisher

Zambelli F, Mertens J, Dziedzicka D, Sterckx J, Markouli C, Keller A, et al. Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells. Stem Cell Reports. 2018;11:102-114 pubmed publisher

Espuny Camacho I, Michelsen K, Linaro D, Bilheu A, Acosta Verdugo S, Herpoel A, et al. Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way. Cell Rep. 2018;23:2732-2743 pubmed publisher

D Abaco G, Mattei C, Nasr B, Hudson E, Alshawaf A, Chana G, et al. Graphene foam as a biocompatible scaffold for culturing human neurons. R Soc Open Sci. 2018;5:171364 pubmed publisher

Amin M, Kushida Y, Wakao S, Kitada M, Tatsumi K, Dezawa M. Cardiotrophic Growth Factor-Driven Induction of Human Muse Cells Into Cardiomyocyte-Like Phenotype. Cell Transplant. 2018;27:285-298 pubmed publisher

Alexeev E, Lanis J, Kao D, Campbell E, Kelly C, Battista K, et al. Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. Am J Pathol. 2018;188:1183-1194 pubmed publisher

Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, et al. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Mol Metab. 2018;9:57-68 pubmed publisher

Li J, Wu X, Zhou Y, Lee M, Guo L, Han W, et al. Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC. Nucleic Acids Res. 2018;46:2883-2900 pubmed publisher

Memon B, Karam M, Al Khawaga S, Abdelalim E. Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1. Stem Cell Res Ther. 2018;9:15 pubmed publisher

Jovanovic V, Salti A, Tilleman H, Zega K, Jukic M, Zou H, et al. BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells. J Neurosci. 2018;38:1662-1676 pubmed publisher

Avaliani N, Pfisterer U, Heuer A, Parmar M, Kokaia M, Andersson M. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus. Stem Cells Int. 2017;2017:5718608 pubmed publisher

Tumelty K, Higginson Scott N, Fan X, Bajaj P, Knowlton K, Shamashkin M, et al. Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein-Gremlin signaling pathways. J Biol Chem. 2018;293:3039-3055 pubmed publisher

Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher

Harper E, Rochfort K, Forde H, Davenport C, Smith D, Cummins P. TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models. PLoS ONE. 2017;12:e0188192 pubmed publisher

Ocaña O, Coskun H, Minguillón C, Murawala P, Tanaka E, Galcerán J, et al. A right-handed signalling pathway drives heart looping in vertebrates. Nature. 2017;549:86-90 pubmed publisher

Cogger K, Sinha A, Sarangi F, McGaugh E, Saunders D, Dorrell C, et al. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors. Nat Commun. 2017;8:331 pubmed publisher

Hegarty S, Wyatt S, Howard L, Stappers E, Huylebroeck D, Sullivan A, et al. Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation. Sci Rep. 2017;7:8568 pubmed publisher

Shao Y, Taniguchi K, Townshend R, Miki T, Gumucio D, Fu J. A pluripotent stem cell-based model for post-implantation human amniotic sac development. Nat Commun. 2017;8:208 pubmed publisher

Múnera J, Sundaram N, Rankin S, Hill D, Watson C, Mahe M, et al. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell Stem Cell. 2017;21:51-64.e6 pubmed publisher

Drouin Ouellet J, Lau S, Brattås P, Rylander Ottosson D, Pircs K, Grassi D, et al. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways. EMBO Mol Med. 2017;9:1117-1131 pubmed publisher

Isshiki H, Arimura Y, Nagaishi K, Kawakami K, Onodera K, Yamashita K, et al. Establishment of a refined culture method for rat colon organoids. Biochem Biophys Res Commun. 2017;489:305-311 pubmed publisher

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, et al. Common genetic variation drives molecular heterogeneity in human iPSCs. Nature. 2017;546:370-375 pubmed publisher

Baronchelli S, La Spada A, Ntai A, Barbieri A, Conforti P, Jotti G, et al. Epigenetic and transcriptional modulation of WDR5, a chromatin remodeling protein, in Huntington's disease human induced pluripotent stem cell (hiPSC) model. Mol Cell Neurosci. 2017;82:46-57 pubmed publisher

Raja E, Komuro A, Tanabe R, Sakai S, Ino Y, Saito N, et al. Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells. Oncogene. 2017;36:4963-4974 pubmed publisher

Yuan X, Li Z, Baines A, Gavriilaki E, Ye Z, Wen Z, et al. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. PLoS ONE. 2017;12:e0174074 pubmed publisher

Bernhardt M, Novak D, Assenov Y, Orouji E, Knappe N, Weina K, et al. Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response. Stem Cell Reports. 2017;8:1379-1391 pubmed publisher

Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, et al. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS ONE. 2017;12:e0171947 pubmed publisher

Barry C, Schmitz M, Jiang P, Schwartz M, Duffin B, Swanson S, et al. Species-specific developmental timing is maintained by pluripotent stem cells ex utero. Dev Biol. 2017;423:101-110 pubmed publisher

McCracken K, Aihara E, Martin B, Crawford C, Broda T, Treguier J, et al. Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature. 2017;541:182-187 pubmed publisher

Du J, Yanagida A, Knight K, Engel A, Vo A, Jankowski C, et al. Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2016;113:14710-14715 pubmed publisher

Xia W, Chen L, Liang J, Zhang X, Su C, Tong X, et al. BMP4/Id2 signaling pathway is a novel therapeutic target for late outgrowth endothelial progenitor cell-mediated endothelial injury repair. Int J Cardiol. 2017;228:796-804 pubmed publisher

Plaisted W, Zavala A, Hingco E, Tran H, Coleman R, Lane T, et al. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. PLoS ONE. 2016;11:e0157620 pubmed publisher

Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher

Nageshappa S, Carromeu C, Trujillo C, Mesci P, Espuny Camacho I, Pasciuto E, et al. Altered neuronal network and rescue in a human MECP2 duplication model. Mol Psychiatry. 2016;21:178-88 pubmed publisher

Dhawan S, Tschen S, Zeng C, Guo T, Hebrok M, MATVEYENKO A, et al. DNA methylation directs functional maturation of pancreatic β cells. J Clin Invest. 2015;125:2851-60 pubmed publisher

Cebola I, Rodríguez Seguí S, Cho C, Bessa J, Rovira M, Luengo M, et al. TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. Nat Cell Biol. 2015;17:615-626 pubmed publisher

Dye B, Hill D, Ferguson M, Tsai Y, Nagy M, Dyal R, et al. In vitro generation of human pluripotent stem cell derived lung organoids. elife. 2015;4: pubmed publisher

Edri R, Yaffe Y, Ziller M, Mutukula N, Volkman R, David E, et al. Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nat Commun. 2015;6:6500 pubmed publisher

Pezzolla D, López Beas J, Lachaud C, Domínguez Rodríguez A, Smani T, Hmadcha A, et al. Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells. PLoS ONE. 2015;10:e0119904 pubmed publisher

Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D Souza S, et al. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc. 2015;10:413-25 pubmed publisher

All A, Gharibani P, Gupta S, Bazley F, Pashai N, Chou B, et al. Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. PLoS ONE. 2015;10:e0116933 pubmed publisher

Hu D, Young N, Li X, Xu Y, Hallgrímsson B, Marcucio R. A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face. Development. 2015;142:567-74 pubmed publisher

Bayin N, Modrek A, Dietrich A, Lebowitz J, Abel T, Song H, et al. Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells. PLoS ONE. 2014;9:e116114 pubmed publisher

Hernanda P, Chen K, Das A, Sideras K, Wang W, Li J, et al. SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma. Oncogene. 2015;34:5055-68 pubmed publisher

Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, et al. Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function. Infect Immun. 2015;83:138-45 pubmed publisher

Pereira M, Pfisterer U, Rylander D, Torper O, Lau S, Lundblad M, et al. Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain. Sci Rep. 2014;4:6330 pubmed publisher

Wattanapanitch M, Klincumhom N, Potirat P, Amornpisutt R, Lorthongpanich C, U Pratya Y, et al. Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages. PLoS ONE. 2014;9:e106952 pubmed publisher

Lee R, Kim I, Han N, Yun S, Park K, Yoo K. Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells. Sci Rep. 2014;4:6319 pubmed publisher

Robson N, Hidalgo L, Mc Alpine T, Wei H, Martínez V, Entrena A, et al. Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling. Cancer Res. 2014;74:5019-5031 pubmed publisher

Pethe P, Nagvenkar P, Bhartiya D. Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro. BMC Cell Biol. 2014;15:18 pubmed publisher

Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, et al. A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium. Stem Cells Transl Med. 2014;3:911-22 pubmed publisher

Thiede B, Mann Z, Chang W, Ku Y, Son Y, Lovett M, et al. Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea. Nat Commun. 2014;5:3840 pubmed publisher

Mann Z, Thiede B, Chang W, Shin J, May Simera H, Lovett M, et al. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun. 2014;5:3839 pubmed publisher

Ali F, Cheng K, Kirwan P, Metcalfe S, Livesey F, Barker R, et al. The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development. 2014;141:2216-24 pubmed publisher

Burnight E, Wiley L, Drack A, Braun T, Anfinson K, Kaalberg E, et al. CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Gene Ther. 2014;21:662-72 pubmed publisher

He Q, Wang G, Wakade S, Dasgupta S, Dinkins M, Kong J, et al. Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. Mol Biol Cell. 2014;25:1715-29 pubmed publisher

Takeuchi H, Nakatsuji N, Suemori H. Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. Sci Rep. 2014;4:4488 pubmed publisher

Heinonen A, Rahman M, Dogbevia G, Jakobi H, Wolfl S, Sprengel R, et al. Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7. BMC Neurosci. 2014;15:38 pubmed publisher

Ronaghi M, Nasr M, Ealy M, Durruthy Durruthy R, Waldhaus J, Diaz G, et al. Inner ear hair cell-like cells from human embryonic stem cells. Stem Cells Dev. 2014;23:1275-84 pubmed publisher

Cai Q, Bonfanti P, Sambathkumar R, Vanuytsel K, Vanhove J, Gysemans C, et al. Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells. Stem Cells Transl Med. 2014;3:489-99 pubmed publisher

Cechin S, Alvarez Cubela S, Giraldo J, Molano R, Villate S, Ricordi C, et al. Influence of in vitro and in vivo oxygen modulation on β cell differentiation from human embryonic stem cells. Stem Cells Transl Med. 2014;3:277-89 pubmed publisher

Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J Am Soc Nephrol. 2014;25:1211-25 pubmed publisher

Lippmann E, Estevez Silva M, Ashton R. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells. 2014;32:1032-42 pubmed publisher

Hannan N, Fordham R, Syed Y, Moignard V, Berry A, Bautista R, et al. Generation of multipotent foregut stem cells from human pluripotent stem cells. Stem Cell Reports. 2013;1:293-306 pubmed publisher

Weedon M, Cebola I, Patch A, Flanagan S, De Franco E, Caswell R, et al. Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Nat Genet. 2014;46:61-64 pubmed publisher

Zhang Y, Liu J, Tian X, Wong W, Chen Y, Wang L, et al. Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice. Arterioscler Thromb Vasc Biol. 2014;34:152-9 pubmed publisher

Dunworth W, Cardona Costa J, Bozkulak E, Kim J, Meadows S, Fischer J, et al. Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos. Circ Res. 2014;114:56-66 pubmed publisher

Lin P, Hung S, Yang Y, Liao L, Hsieh Y, Yen H, et al. A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells. Stem Cells Dev. 2014;23:372-9 pubmed publisher

Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed publisher

Talavera Adame D, Gupta A, Kurtovic S, Chaiboonma K, Arumugaswami V, Dafoe D. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev. 2013;22:3252-60 pubmed publisher

Rezania A, Bruin J, Xu J, Narayan K, Fox J, O Neil J, et al. Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells. 2013;31:2432-42 pubmed publisher

Jiang J, Jing Y, Cost G, Chiang J, Kolpa H, Cotton A, et al. Translating dosage compensation to trisomy 21. Nature. 2013;500:296-300 pubmed publisher

Maroof A, Keros S, Tyson J, Ying S, Ganat Y, Merkle F, et al. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell. 2013;12:559-72 pubmed publisher

Buchholz D, Pennington B, Croze R, Hinman C, Coffey P, Clegg D. Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Transl Med. 2013;2:384-93 pubmed publisher

Farmer J, Altschaefl K, O Shea K, Miller D. Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation. PLoS ONE. 2013;8:e58813 pubmed publisher

Tucker B, Anfinson K, Mullins R, Stone E, Young M. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med. 2013;2:16-24 pubmed publisher

Brafman D, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death Differ. 2013;20:369-81 pubmed publisher

Swapna I, Borodinsky L. Interplay between electrical activity and bone morphogenetic protein signaling regulates spinal neuron differentiation. Proc Natl Acad Sci U S A. 2012;109:16336-41 pubmed publisher

Li Q, Ramirez Bergeron D, Dunwoodie S, Yang Y. Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene. J Biol Chem. 2012;287:29088-100 pubmed publisher

Maegdefrau U, Arndt S, Kivorski G, Hellerbrand C, Bosserhoff A. Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma. Lab Invest. 2011;91:1615-23 pubmed publisher

Spence J, Mayhew C, Rankin S, Kuhar M, Vallance J, Tolle K, et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature. 2011;470:105-9 pubmed publisher

Klim J, Li L, Wrighton P, Piekarczyk M, Kiessling L. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat Methods. 2010;7:989-94 pubmed publisher