product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CLEC9a Fc Chimera Protein, CF
catalog :
6049-CL-050
quantity :
50 ug
price :
447 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Eggink L, Roby K, Cote R, Kenneth Hoober J. An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides. J Immunother Cancer. 2018;6:28 pubmed publisher
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
Iborra S, Izquierdo H, Martínez López M, Blanco Menéndez N, Reis E Sousa C, Sancho D. The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice. J Clin Invest. 2012;122:1628-43 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
6049-CL
SKU :
6049-CL-050
product name :
Recombinant Human CLEC9a Fc Chimera Protein, CF
Description :
The Recombinant Human CLEC9a Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CLEC9a Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CLEC9a
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
55-65 kDa, reducing conditions
theoretical molecular weight :
47.8 kDa (monomer)
gene symbol :
CLEC9A
details of functionality :
Measured by flow cytometry for its ability to bind a ligand expressed in FasL-treated mouse B cells. Sancho, D. et al . (2009) Nature 458 :899. At 100 ng/mL, 50% of necrotic cells bind to Recombinant Human CLEC9a.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q6UXN8
applications :
Bioactivity
source :
NS0-derived Recombinant Human CLEC9a Fc Chimera Protein
USD :
447 USD
alt names :
CD370, C-type lectin domain family 9 member A, C-type lectin domain family 9, member A, DNGR1, HEEE9341, UNQ9341
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.