Recombinant Human IDO Protein, CF | R&D Systems 6030-AO-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IDO Protein, CF

catalog :

6030-AO-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Donley D, Realing M, Gigley J, Fox J. Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease. PLoS ONE. 2021;16:e0250606 pubmed publisher
Jonescheit H, Oberg H, Gonnermann D, Hermes M, Sulaj V, Peters C, et al. Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells. Cells. 2020;9: pubmed publisher
Bracho Sanchez E, Hassanzadeh A, Brusko M, Wallet M, Keselowsky B. Dendritic Cells Treated with Exogenous Indoleamine 2,3-Dioxygenase Maintain an Immature Phenotype and Suppress Antigen-specific T cell Proliferation. J Immunol Regen Med. 2019;5: pubmed publisher

product information

master code :

6030-AO

SKU :

6030-AO-010

product name :

Recombinant Human IDO Protein, CF

unit size :

10 ug

description :

The Recombinant Human IDO Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IDO Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Indoleamine 2,3-dioxygenase/IDO

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Sodium Acetate, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

42 kDa, reducing conditions

theoretical molecular weight :

46 kDa

gene symbol :

IDO1

details of functionality :

Measured by its ability to oxidize L-tryptophan to N-formyl-kynurenine. The specific activity is 500 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P14902

applications :

Enzyme Activity

source long :

E. coli -derived human Indoleamine 2,3-dioxygenase/IDO protein M HHHHHH Human IDO (Ala2-Gly403) Accession # P14902 N-terminus C-terminus

source short :

E. coli

extended description :

Indoleamine 2,3-dioxygenase

USD :

432 USD

product details :

Indoleamine 2,3-dioxygenase

alt names :

3dioxygenase, EC 1.13.11.52, IDO, IDO1, IDOIDO-1, INDO, INDOindole 2,3-dioxygenase, Indoleamine 2, indoleamine 2,3-dioxygenase 1, indoleamine-pyrrole 2,3 dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage