Recombinant Mouse Neuropilin-1 Protein, CF | R&D Systems 5994-N1-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Neuropilin-1 Protein, CF

catalog :

5994-N1-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Muhl L, Folestad E, Gladh H, Wang Y, Moessinger C, Jakobsson L, et al. Neuropilin 1 binds PDGF-D and is a co-receptor in PDGF-D-PDGFR? signaling. J Cell Sci. 2017;130:1365-1378 pubmed publisher
Teran M, Nugent M. Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity. J Biol Chem. 2015;290:16451-62 pubmed publisher
Delgoffe G, Woo S, Turnis M, Gravano D, Guy C, Overacre A, et al. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature. 2013;501:252-6 pubmed publisher
Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H. Osteoprotection by semaphorin 3A. Nature. 2012;485:69-74 pubmed publisher

product information

master code :

5994-N1

SKU :

5994-N1-050

product name :

Recombinant Mouse Neuropilin-1 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Neuropilin-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Neuropilin-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Neuropilin-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

100-120 kDa, reducing conditions

theoretical molecular weight :

94.5 kDa (monomer)

gene symbol :

Nrp1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse Neuropilin-1 can bind recombinant human VEGF165 with an apparent KD 1 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_032763

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Neuropilin-1 protein Phe22-Pro856, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

BDCA4, BDCA-4, CD304, CD304 antigen, DKFZp686A03134, DKFZp781F1414, neuropilin 1, neuropilin-1, Neuropilin1, NP1, NRP, NRP1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage