Recombinant Mouse CXCL4/PF4 Protein, CF | R&D Systems 595-P4-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CXCL4/PF4 Protein, CF

catalog :

595-P4-025

quantity :

25 ug

price :

294 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Graça F, Stephan A, Minden Birkenmaier B, Shirinifard A, Wang Y, Demontis F, et al. Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles. Nat Commun. 2023;14:2900 pubmed publisher
Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed publisher
Drescher H, Brandt E, Fischer P, Dreschers S, Schwendener R, Kowalska M, et al. Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice. Front Physiol. 2019;10:326 pubmed publisher
Kuroishi T, Bando K, Tanaka Y, Shishido K, Kinbara M, Ogawa T, et al. CXCL4 is a novel nickel-binding protein and augments nickel allergy. Clin Exp Allergy. 2017;47:1069-1078 pubmed publisher
de Jong E, de Haas A, Brouwer N, van Weering H, Hensens M, Bechmann I, et al. Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3. J Neurochem. 2008;105:1726-36 pubmed publisher
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed

image

image 1 :

Recombinant Mouse CXCL4/PF4 Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

595-P4

SKU :

595-P4-025

product name :

Recombinant Mouse CXCL4/PF4 Protein, CF

Description :

The Recombinant Mouse CXCL4/PF4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL4/PF4 Protein, CF has been validated for the following applications: Binding Activity.

target :

CXCL4/PF4

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

8.2 kDa

gene symbol :

Pf4

details of functionality :

Measured by its ability to inhibit the FGF basic-dependent proliferation of HUVEC human umbilical vein endothelial cells. Dubrac, A. et al . (2010) Blood 116 :4703. The ED50 for this effect is 2-10 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9Z126

applications :

Binding Activity

source :

E. coli-derived Recombinant Mouse CXCL4/PF4 Protein

USD :

294 USD

alt names :

chemokine (C-X-C motif) ligand 4, C-X-C motif chemokine 4, CXCL4iroplact, Iroplact, MGC138298, Oncostatin-A, PF4, PF-4, platelet factor 4, SCYB4oncostatin-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage