Recombinant Mouse CXCL4/PF4 Protein, CF | R&D Systems 595-P4-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CXCL4/PF4 Protein, CF

catalog :

595-P4-025

quantity :

25 ug

price :

300 USD

citations: 6

Reference
Graça F, Stephan A, Minden Birkenmaier B, Shirinifard A, Wang Y, Demontis F, et al. Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles. Nat Commun. 2023;14:2900 pubmed publisher
Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed publisher
Drescher H, Brandt E, Fischer P, Dreschers S, Schwendener R, Kowalska M, et al. Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice. Front Physiol. 2019;10:326 pubmed publisher
Kuroishi T, Bando K, Tanaka Y, Shishido K, Kinbara M, Ogawa T, et al. CXCL4 is a novel nickel-binding protein and augments nickel allergy. Clin Exp Allergy. 2017;47:1069-1078 pubmed publisher
de Jong E, de Haas A, Brouwer N, van Weering H, Hensens M, Bechmann I, et al. Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3. J Neurochem. 2008;105:1726-36 pubmed publisher
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed

product information

master code :

595-P4

SKU :

595-P4-025

product name :

Recombinant Mouse CXCL4/PF4 Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse CXCL4/PF4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL4/PF4 Protein, CF has been validated for the following applications: Binding Activity.

target :

CXCL4/PF4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

8.2 kDa

gene symbol :

Pf4

details of functionality :

Measured by its ability to inhibit the FGF basic-dependent proliferation of HUVEC human umbilical vein endothelial cells. Dubrac, A. et al . (2010) Blood 116 :4703. The ED50 for this effect is 2-10 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse CXCL4/PF4 Protein Bioactivity

accessionNumbers :

Q9Z126

applications :

Binding Activity

source long :

E. coli -derived mouse CXCL4/PF4 protein Val30-Ser105

source short :

E. coli

USD :

300 USD

alt names :

chemokine (C-X-C motif) ligand 4, C-X-C motif chemokine 4, CXCL4iroplact, Iroplact, MGC138298, Oncostatin-A, PF4, PF-4, platelet factor 4, SCYB4oncostatin-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.