product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF
catalog :
593-BC-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, et al. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement. PLoS ONE. 2014;9:e91857 pubmed publisher
Kimberley F, van der Sloot A, Guadagnoli M, Cameron K, Schneider P, Marquart J, et al. The design and characterization of receptor-selective APRIL variants. J Biol Chem. 2012;287:37434-46 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
593-BC
SKU :
593-BC-050
product name :
Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF
description :
The Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
BCMA/TNFRSF17
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
35-40 kDa, reducing conditions
theoretical molecular weight :
32 kDa (monomer)
gene symbol :
Tnfrsf17
details of functionality :
Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. Moore, P.A. et al . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider, P. et al . (1999) J. Exp. Med. 189 :1747. The ED50 for this effect is 0.01-0.03 µg/mL in the presence of 100 ng/mL of rhAPRIL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_035738
applications :
Bioactivity
product keywords :
593-BC, rmBCMA/Fc, mBCMA, carrier-free, carrier free, 593BC, TNFRSF 17, cytokine, cytokines, cytokine receptor, cytokine receptors, sCD269, sBCMA, BCMA/TNFRSD17, TNF Receptor Superfamily Member 17, B-Cell Maturation Protein, BCM, B Cell Maturation Antigen, CD269 Antigen, TNFRSF13A
source :
NS0-derived Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF
USD :
423
USD 2025 :
432 USD
alt names :
B cell maturation antigen, B-cell maturation protein, BCMAtumor necrosis factor receptor superfamily member 17, BCMB-cell maturation factor, CD269, CD269 antigen, TNFRSF13A, TNFRSF17, tumor necrosis factor receptor superfamily, member 17
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.