Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF | R&D Systems 593-BC-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF

catalog :

593-BC-050

quantity :

50 ug

price :

432 USD

citations: 3

Reference
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, et al. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement. PLoS ONE. 2014;9:e91857 pubmed publisher
Kimberley F, van der Sloot A, Guadagnoli M, Cameron K, Schneider P, Marquart J, et al. The design and characterization of receptor-selective APRIL variants. J Biol Chem. 2012;287:37434-46 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher

product information

master code :

593-BC

SKU :

593-BC-050

product name :

Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BCMA/TNFRSF17 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

BCMA/TNFRSF17

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

35-40 kDa, reducing conditions

theoretical molecular weight :

32 kDa (monomer)

gene symbol :

Tnfrsf17

details of functionality :

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. Moore,áP.A. etáal . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider,áP. etáal . (1999) J. Exp. Med. 189 :1747. The ED50 for this effect is 0.01-0.03 ╡g/mL in the presence of 100 ng/mL of rhAPRIL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_035738

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse BCMA/TNFRSF17 protein Mouse BCMA (Met1 - Thr49) Accession # NP_035738 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

B cell maturation antigen, B-cell maturation protein, BCMAtumor necrosis factor receptor superfamily member 17, BCMB-cell maturation factor, CD269, CD269 antigen, TNFRSF13A, TNFRSF17, tumor necrosis factor receptor superfamily, member 17

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.