product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse sFRP-3 Protein, CF
catalog :
592-FR-010/CF
quantity :
10 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 6
Reference
Chen C, Yang Y, Yao Y. HBO Promotes the Differentiation of Neural Stem Cells via Interactions Between the Wnt3/β-Catenin and BMP2 Signaling Pathways. Cell Transplant. 2019;28:1686-1699 pubmed publisher
Li B, Shi Y, Shu J, Gao J, Wu P, Tang S. Wingless-type mammary tumor virus integration site family, member 5A (Wnt5a) regulates human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein 120 (gp120)-induced expression of pro-inflammatory cytokines via the Ca2+/calmodulin-dependent pr. J Biol Chem. 2013;288:13610-9 pubmed publisher
Jang M, Bonaguidi M, Kitabatake Y, Sun J, Song J, Kang E, et al. Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell. 2013;12:215-23 pubmed publisher
Wawrzak D, Metioui M, Willems E, Hendrickx M, De Genst E, Leyns L. Wnt3a binds to several sFRPs in the nanomolar range. Biochem Biophys Res Commun. 2007;357:1119-23 pubmed
Person A, Garriock R, Krieg P, Runyan R, Klewer S. Frzb modulates Wnt-9a-mediated beta-catenin signaling during avian atrioventricular cardiac cushion development. Dev Biol. 2005;278:35-48 pubmed
Polesskaya A, Seale P, Rudnicki M. Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell. 2003;113:841-52 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
592-FR/CF
SKU :
592-FR-010/CF
product name :
Recombinant Mouse sFRP-3 Protein, CF
Description :
The Recombinant Mouse sFRP-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse sFRP-3 Protein, CF has been validated for the following applications: Bioactivity.
target :
sFRP-3
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
37 kDa, reducing conditions
theoretical molecular weight :
34 kDa
gene symbol :
Frzb
details of functionality :
Measured by its ability to inhibit proliferation in MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 1.5-6.0 µg/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P97401
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse sFRP-3 Protein
USD :
423 USD
alt names :
FIZ, FREOS1, Frezzled, Fritz, frizzled-related protein, Frizzled-related protein 1, FRP, FRP-3, FRZB, Frzb1, FrzB-1, FRZB1sFRP-3, FRZB-PEN, FZRB, hFIZ, secreted frizzled-related protein 3, sFRP3, SFRP3frezzled, SRFP3frizzled homolog-related
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.