product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Mer Fc Chimera Protein, CF
catalog :
591-MR-100
quantity :
100 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Lee Y, Park H, Woo S, Park E, Kang J. RhoA/phosphatidylinositol 3-kinase/protein kinase B/mitogen-activated protein kinase signaling after growth arrest-specific protein 6/mer receptor tyrosine kinase engagement promotes epithelial cell growth and wound repair via upregulation of hepatoc. J Pharmacol Exp Ther. 2014;350:563-77 pubmed publisher
Galvan M, Foreman D, Zeng E, Tan J, Bohlson S. Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells. J Immunol. 2012;188:3716-23 pubmed publisher
Sather S, Kenyon K, Lefkowitz J, Liang X, Varnum B, Henson P, et al. A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. Blood. 2007;109:1026-33 pubmed
product information
master code :
591-MR
SKU :
591-MR-100
product name :
Recombinant Mouse Mer Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Mouse Mer Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse Mer Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Mer
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
110-115 kDa, reducing conditions
theoretical molecular weight :
78.7 kDa (monomer)
gene symbol :
Mertk
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized rmMer/Fc Chimera at 10 ╡g/mL (100 ╡L/well) can bind rhGas6 with a linear range of 0.03-1 ╡g/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q60805
applications :
Binding Activity
source long :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse Mer protein Mouse Mer (Glu23 - Phe498) Accession # Q60805 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
Sf 21 (baculovirus)
USD :
468 USD
alt names :
c-Eyk, C-mer, c-mer proto-oncogene tyrosine kinase, EC 2.7.10, EC 2.7.10.1, MER, MER receptor tyrosine kinase, MerTK, MGC133349, Receptor tyrosine kinase MerTK, RP38Proto-oncogene c-Mer, STK kinase, tyrosine-protein kinase Mer
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.