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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Dkk-1 Protein, CF
catalog :
5897-DK-010/CF
quantity :
10 ug
price :
432 USD
more info or order :
citations: 49
Reference
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Cai X, Xie J, Yao Y, Cun X, Lin S, Tian T, et al. Angiogenesis in a 3D model containing adipose tissue stem cells and endothelial cells is mediated by canonical Wnt signaling. Bone Res. 2017;5:17048 pubmed publisher
Gu D, Wang S, Zhang S, Zhang P, Zhou G. Directed transdifferentiation of Müller glial cells to photoreceptors using the sonic hedgehog signaling pathway agonist purmorphamine. Mol Med Rep. 2017;16:7993-8002 pubmed publisher
Susman M, Karuna E, Kunz R, Gujral T, Cantú A, Choi S, et al. Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. elife. 2017;6: pubmed publisher
Tassew N, Charish J, Shabanzadeh A, Luga V, Harada H, Farhani N, et al. Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS. Cell Rep. 2017;20:99-111 pubmed publisher
Tammela T, Sanchez Rivera F, Cetinbas N, Wu K, Joshi N, Helenius K, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545:355-359 pubmed publisher
Wilk K, Yeh S, Mortensen L, Ghaffarigarakani S, Lombardo C, Bassir S, et al. Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration. Stem Cell Reports. 2017;8:933-946 pubmed publisher
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Zhang J, Zhang J, Qi C, Yang P, Chen X, Liu Y. Activation of Wnt3?/?-catenin signal pathway attenuates apoptosis of the cerebral microvascular endothelial cells induced by oxygen-glucose deprivation. Biochem Biophys Res Commun. 2017;490:71-77 pubmed publisher
Himburg H, Doan P, Quarmyne M, Yan X, Sasine J, Zhao L, et al. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat Med. 2017;23:91-99 pubmed publisher
Muruganandan S, Govindarajan R, McMullen N, Sinal C. Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation. Stem Cells. 2017;35:711-724 pubmed publisher
Saleh F, Carstairs A, Etheridge S, Genever P. Real-Time Analysis of Endogenous Wnt Signalling in 3D Mesenchymal Stromal Cells. Stem Cells Int. 2016;2016:7132529 pubmed publisher
Yin X, Yi H, Wang L, Wu W, Wu X, Yu L. RSPOs facilitated HSC activation and promoted hepatic fibrogenesis. Oncotarget. 2016;7:63767-63778 pubmed publisher
Esen E, Lee S, Wice B, Long F. PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling. J Bone Miner Res. 2015;30:1959-68 pubmed publisher
Caruso M, Ferranti F, Corano Scheri K, Dobrowolny G, Ciccarone F, Grammatico P, et al. R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis. PLoS ONE. 2015;10:e0124213 pubmed publisher
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product information
master code :
5897-DK/CF
SKU :
5897-DK-010/CF
product name :
Recombinant Mouse Dkk-1 Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse Dkk-1 Protein, CF from R&D Systems is derived from CHO.
target :
Dkk-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
35-40 kDa, reducing conditions
theoretical molecular weight :
26.1 kDa
gene symbol :
Dkk1
details of functionality :
Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. Recombinant Mouse Dkk-1 (Catalog # 5897-DK/CF) inhibits a constant dose of 100 ng/mL of Recombinant Human Wnt-3a (Catalog # 1324-WN ). The ED50 for this effect is 10-60 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse Dkk-1 Protein Bioactivity
accessionNumbers :
O54908
source long :
Chinese Hamster Ovary cell line, CHO-derived mouse Dkk-1 protein Ser30-His272
source short :
CHO
USD :
432 USD
alt names :
dickkopf (Xenopus laevis) homolog 1, dickkopf homolog 1 (Xenopus laevis), dickkopf related protein-1, Dickkopf-1, dickkopf-related protein 1, Dkk1, DKK-1, hDkk-1, SKdickkopf-1 like
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.