Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF | R&D Systems 587-RI-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF

catalog :

587-RI-050

quantity :

50 ug

price :

456 USD

citations: 2

Reference
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher
Niessen K, Zhang G, Ridgway J, Chen H, Yan M. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood. 2010;115:1654-61 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

587-RI

SKU :

587-RI-050

product name :

Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF

description :

The Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TGF-beta RI/ALK-5

unit size :

50 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

40-50 kDa, reducing conditions

theoretical molecular weight :

37.5 kDa (monomer)

gene symbol :

Tgfbr1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Rat Endoglin/CD105 Fc Chimera (Catalog # 6440-EN ) or Recombinant Mouse Endoglin/CD105 Fc Chimera (Catalog # 1320-EN ) is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse TGF¿ß RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 µg/mL.

endotoxin note :

<0.1 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

BAA05023

applications :

Bioactivity

product keywords :

587-RI, rmTGF-b RI/Fc, mTGF-b RI, carrier-free, carrier free, 587RI, TGF-bRI, TGFbetaRI, TGF- RI, TGF- RI, TGF b RI, TGF-b RI, TGF-bR I, TGF-bR1, TGF-beta R1, TGF b R1, TGF-b R1, TGF-bR 1, TGF beta RI, TGF-betaRI, TGF-ssR1, TGF-ss R1, TGF-ss RI, TGF-beta Receptor I, Transforming Growth Factor beta Receptor I, Color

source :

Sf 21 (baculovirus)-derived Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF

extended description :

This item is in process of being discontinued.

USD :

447

USD 2025 :

456 USD

product details :

This item is in process of being discontinued.

alt names :

AAT5, activin A receptor type II-like kinase, 53kD, activin A receptor type II-like kinase, 53kDa, Activin receptor-like kinase 5, ACVRLK4, ALK-5, ALK-5ALK5, EC 2.7.11, EC 2.7.11.30, LDS1A, LDS2A, Serine/threonine-protein kinase receptor R4, SKR4, TbetaR-I, TGFB1R1, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFbetaRI, TGFBR1, TGF-bRI, TGFR-1, transforming growth factor beta receptor I, transforming growth factor, beta receptor 1, transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD), Transforming growth factor-beta receptor type I